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GO:0043526neuroprotectionPMID:22384090IMP: Inferred from Mutant Phenotype P
This annotation made on page:
By: Hilaryann0524 (group Team Unicorn) on 2012-03-07 12:26:40 CST.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeImumm,
Team IT
2012-03-20 19:39:26 CDT

Figure 1 does not prove that loss of Bmi1 expression results in the consequent loss of neurons, but only shows that Bmi1 expression is lost as a result of aging. I also believe that the evidence code should be IDA not IMP, because the levels of antibodies targeted were not depleted. Instead the antibodies were targeted in Bmi1 through immunohistochemistry (IHC) with no intent of changing the protein's function. Then PCR was used to detect the loss of expression in Bmi1.

3
Private
Assessment
Sgouni2012-03-20 20:20:34 CDTYou need to be an instructor to view these notes.Unacceptable