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Cacao
GO:0048023 | positive regulation of melanin biosynthetic process | PMID:21949658 | IGI: Inferred from Genetic Interaction UniProtKB:P07147 UniProtKB:Q60696 | P | ||||
This annotation made on page: MOUSE:ASIP By: Emlarkin03 (group Team Angry Squirrels) on 2011-10-18 19:54:26 CDT. |
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Entry Type | Challenging User,Group | Time/Date | Challenge Reason | Points/Assessment |
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Challenge | Lrodgers, Team KremlinOnTheCrum | 2011-10-25 21:57:09 CDT | The evidence code should be IMP because the table is only comparing WT to -/- PMEL mutant. | 0 |
Public Assessment | Bmcintosh | 2011-11-18 13:40:19 CST | We agree with the original annotation - the authors state "No consistent difference in pheomelanin-content was noted among Pmel genotypes; by comparison, homozygosity for the non-agouti allele at the Asip locus caused a drastic reduction in pheomelanin content (Table 2)." Thus, it takes mutations in more than 1 gene to see the altered phenotype. | Acceptable |