GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Cacao
GO:0043085 | positive regulation of catalytic activity | PMID:21909421 | IDA: Inferred from Direct Assay | P | ||||
This annotation made on page: By: Mdao3 (group Team That Will Beat You!!!) on 2011-10-09 16:23:01 CDT. |
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Entry Type | Challenging User,Group | Time/Date | Challenge Reason | Points/Assessment |
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Challenge | Sejal, Team UCL-Maple Leafs | 2011-10-16 15:11:38 CDT | In figure 3, another possible GO term can be `transcription from RNA polymerase II promoter` (GO:0006366). Figure 3A, Luciferase activity was measured by using two different constructs of FUS (FUS-N and FUS-C), both fragments displayed activities compared to full length of FUS. | 5 |
Private Assessment | Mkline | 2012-03-27 12:13:32 CDT | You need to be an instructor to view these notes. | Acceptable |
Public Assessment | Davidmigl | 2011-10-18 20:29:40 CDT | "Positive regulation of catalytic activity" is a term that applies to regulation of enzymes. The protein in question is transcriptional co-activator, not an enzyme, so Mdao3's annotation is incorrect. 5 points awarded to challenging team for both identifying a problem and suggesting a solution. However, I would add that a better term would be GO:0003713, since FUS is not acting as a transcription factor but a transcriptional co-activator. | Requires Changes |