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GO:0000900translation repressor activity, mRNA regulatory element bindingPMID:29635389IMP: Inferred from Mutant Phenotype F
This annotation made on page: DROME:RB27C
By: Stavana (group Team Translate) on 2018-04-13 19:13:25 CDT.



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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
Private
Assessment
Sandyl 272018-05-23 13:52:01 CDTYou need to be an instructor to view these notes.Updated by Instructor
Protein
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Go term
Evidence
With/From
Notes
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Public
Assessment
Sandyl 272018-04-23 12:16:48 CDT

I'm leaning more towards GO:0045947 and maybe the parent term GO:0030371

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Public
Assessment
DanielRenfro2018-04-22 18:30:41 CDT

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:1903502 translation repressor complex PMID:29635389 IMP: Inferred from Mutant Phenotype C They depleted Hrp48 from SL2 cells and tested the ability of exogenous SXL to inhibit the translation of a reporter containing full-length msl-2 5′ and 3′ UTRs (Figure 3A). Depletion of Hrp48 indeed reduced the capacity of SXL to inhibit translation of the reporter (Figure 3B). The results of this paper support a model where a repressor complex composed of SXL, UNR and Hrp48 assembles at the 3′ UTR of msl-2 mRNA; Hrp48 then contributes to inhibit ribosome recruitment by targeting eIF3d.(Figure 8) complete
CACAO 13242
on DROME:RB27C
Flagged
Private
Assessment
Sandyl 272018-04-16 12:28:49 CDTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Qualifier
With/From
Unique/Original