GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Cacao
| GO:0020002 | host cell plasma membrane | PMID:26471254 | IDA: Inferred from Direct Assay | C | ||||
| This annotation made on page: BPMD2:HOLIN By: Varillaz (group Team Phergalicious) on 2017-04-26 19:56:16 CDT. | ||||||||
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| Entry Type | Challenging User,Group | Time/Date | Challenge Reason | Points/Assessment |
|---|---|---|---|---|
| Challenge | Kvieira, Team Drexel 17A | 2017-05-11 11:33:01 CDT | The chosen report does not support holin as a cellular component of the host cell plasma membrane. However, it does show that coexpression with gp10, and endolysin, results in increased bacterial cell lysis. Therefore, a better GO ID might be GO:0044659 for "cytolysis by virus of host cell". Fig 2e of the same paper shows that the density of the bacteria decreases in the vector containing gp10(endolysin) and gp11 (holin), as compared to a vector containing just gp10, thus supporting gp11 involvement in host cell lysis. | None, yet. |
| Public Assessment | DanielRenfro | 2017-05-11 11:33:01 CDT | This annotation has been flagged because it has been challenged since last assessment | Flagged |
| Public Assessment | AAJohnson | 2017-05-07 17:57:00 CDT | I don't see anything in this figure that suggests the recombinantly expressed proteins are present in the membrane of the host cell. | Requires Changes ✗ Go term ✗ Notes |
