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GO:0001217 | bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding | PMID:12426390 | IDA: Inferred from Direct Assay | F | ||||
This annotation made on page: BPPH2:NP By: Puglisk1 (group Team Blue-B) on 2017-04-23 15:59:40 CDT. |
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Entry Type | Challenging User,Group | Time/Date | Challenge Reason | Points/Assessment |
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Private Assessment | Ivanerill | 2017-05-25 05:07:42 CDT | You need to be an instructor to view these notes. | Updated by Instructor ✔ Protein ✔ Publication ✔ Qualifier ✔ Go term ✔ Evidence ✔ With/From ✔ Notes ✔ Unique/Original |
Public Assessment | Ivanerill | 2017-05-24 06:08:08 CDT | The next figure could be used to annotate GO:0010944 negative regulation of transcription by competitive promoter binding | Requires Changes |
Public Assessment | Ivanerill | 2017-05-24 04:27:23 CDT | One must assume the note refers to Figure 5, which shows competitive binding assays with RNAP, p4, p6 and p46 complex. These demonstrate that p4/6 competes for binding on the promoter with RNAP, effectively preventing RNAP binding and thereby repressing expression. Ideally, the annotation would carry p4 in the WITH field, since it is the complex that has repressor binding function. Alternatively, an identical annotation could be made for p4. | Requires Changes ✔ Protein ✔ Publication ✔ Qualifier ✔ Go term ✔ Evidence ✗ With/From ✗ Notes ✔ Unique/Original |