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GO:0001217bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA bindingPMID:12426390IDA: Inferred from Direct Assay F
This annotation made on page: BPPH2:NP
By: Puglisk1 (group Team Blue-B) on 2017-04-23 15:59:40 CDT.



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Team Blue-B0




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
Private
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Ivanerill2017-05-25 05:07:42 CDTYou need to be an instructor to view these notes.Updated by Instructor
Protein
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With/From
Notes
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Ivanerill2017-05-24 06:08:08 CDT

The next figure could be used to annotate GO:0010944 negative regulation of transcription by competitive promoter binding

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Public
Assessment
Ivanerill2017-05-24 04:27:23 CDT

One must assume the note refers to Figure 5, which shows competitive binding assays with RNAP, p4, p6 and p46 complex. These demonstrate that p4/6 competes for binding on the promoter with RNAP, effectively preventing RNAP binding and thereby repressing expression. Ideally, the annotation would carry p4 in the WITH field, since it is the complex that has repressor binding function. Alternatively, an identical annotation could be made for p4.

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Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original