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Cacao

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GO:0098015virus tailPMID:16054667IMP: Inferred from Mutant Phenotype C
This annotation made on page: BPT7:GP73
By: RajivRangan (group Team Mu) on 2016-04-18 06:00:55 CDT.



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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeNadezdha.Hughes,
Team Tiger2
2016-05-01 13:27:58 CDT

As displayed on the GO definition page, this term is not allowed for annotation. Instead, a parent or child term should be used. The table used as evidence only suggests the final functions suggested by the authors. It does not prove the function through experimental evidence. I suggest using the parent term of virion. However, this may be too broad of a term to use. You can attempt to request an adsorption term. Or, use Figure 4 to annotate the term "virus tail fiber assembly." Though it does not function as a tail fiber itself, it may have a part in their assembly. This can be seen in the discussion and Figure 4.

Discussion-Suggests possible "factor in tail assembly" and gene "perhaps forms a scaffold around gp11 and gp12 polymerize."

Figure 4-Virions that lack the tail fiber gp17 also lack gp7.3

None, yet.
Private
Assessment
Suzialeksander2016-06-27 16:28:13 CDTYou need to be an instructor to view these notes.Updated by Instructor
Private
Assessment
Suzialeksander2016-05-25 15:43:57 CDTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Qualifier
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Evidence
With/From
Notes
Unique/Original
Public
Assessment
DanielRenfro2016-05-06 16:55:16 CDT

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0019012 virion PMID:16054667 IMP: Inferred from Mutant Phenotype C Table 3: Head-less viral particles (tail proteins alone) contained gp7.3, while Tail-less viral particles (head proteins alone) did not contain gp7.3. This suggests that gp7.3 is a protein associated with the viral tail fibers. gp7.3, however, is unlikely to be part of the tail fiber itself as tail fibers produced in vitro without gp7.3 are identical to those of a mature wt virion. complete
CACAO 11761
on BPT7:GP73
Flagged
Public
Assessment
DanielRenfro2016-05-01 13:27:58 CDT

This annotation has been flagged because it has been challenged since last assessment

Flagged
Public
Assessment
Suzialeksander2016-04-26 20:46:23 CDT

No annotation to "part" terms. Look at the term in any browser- you'll see a line about

Restrictions: This term should not be used for direct annotation. See comment below for further information.

Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.

http://www.ebi.ac.uk/QuickGO/GTerm?id=GO:0044423

Requires Changes
Go term
Public
Assessment
DanielRenfro2016-04-26 19:48:27 CDT

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0044423 virion part PMID:16054667 IMP: Inferred from Mutant Phenotype C Table 3: Head-less viral particles (tail proteins alone) contained gp7.3, while Tail-less viral particles (head proteins alone) did not contain gp7.3. This suggests that gp7.3 is a protein associated with the viral tail fibers. gp7.3, however, is unlikely to be part of the tail fiber itself as tail fibers produced in vitro without gp7.3 are identical to those of a mature wt virion. complete
CACAO 11761
on BPT7:GP73
Flagged
Public
Assessment
DanielRenfro2016-04-26 19:22:08 CDT

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0044423 virion part PMID:16054667 IMP: Inferred from Mutant Phenotype C Phage T7 mutants lacking tail fibers were found to also be lacking gp7.3. This suggests that gp7.3 is a component of the tail. complete
CACAO 11761
on BPT7:GP73
Flagged
Public
Assessment
AAJohnson2016-04-26 18:43:09 CDT

The annotation might be a stretch. The paper says the logic can't be correct for this protein to be a tail fiber. The paper shows the protein is required for virus adsorption, and possibly involved in phage assembly. The authors speculate in the discussion about possible function, but it remains undefined. This annotation could be corrected by going up a level in GO and using "virion part" as the cellular component. The student should identify the evidence that supports that annotation.

Requires Changes
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original