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Cacao

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GO:0045916negative regulation of complement activationPMID:8557634IMP: Inferred from Mutant Phenotype P
This annotation made on page: STRPY:Q54958
By: Hannah.Wagner (group Team I'm bringing sexy bacterium) on 2016-04-11 10:02:08 CDT.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeHeidi.Larson.1,
Team Grapes of Staph
2016-04-04 21:06:23 CDT

I would use this Go term for your protein. SIC (Streptococcal inhibitor of complement-mediated lysis) prevents lysis by complement. GO:0045916 is for the negative regulation of the complement cascade. In this study, it mentions that both the classical and the alternative pathways were affected. You could try either of the child terms for GO:0045916. They are GO:0045959 (classical pathway inhibition) and GO:0045957 (alternative pathway inhibition).

0
Private
Assessment
Suzialeksander2016-06-13 15:52:14 CDTYou need to be an instructor to view these notes.Unacceptable
Private
Assessment
Suzialeksander2016-04-11 16:16:02 CDTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Public
Assessment
DanielRenfro2016-04-11 10:02:09 CDT

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0045916 negative regulation of complement activation PMID:8557634 IMP: Inferred from Mutant Phenotype P Figure 9 shows that protein SIC binds to complement C5b-C9 when diluted SIC and a different protein did not. complete
CACAO 11442
on STRPY:Q54958
Flagged
Public
Assessment
DanielRenfro2016-04-04 21:06:23 CDT

This annotation has been flagged because it has been challenged since last assessment

Flagged
Private
Assessment
Suzialeksander2016-04-01 09:32:44 CDTYou need to be an instructor to view these notes.Requires Changes
Go term
Private
Assessment
Min.lorna2016-03-29 19:46:09 CDTYou need to be an instructor to view these notes.Flagged