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GO:0004146dihydrofolate reductase activityGO REF:0000100ISA: Inferred from Sequence Alignment PMID:6815178 UniProtKB:P0ABQ4 F
This annotation made on page: 9CAUD:S5Y0G6
By: Hasli (group TeamPurple) on 2015-04-06 10:50:38 CDT.



TeamPoints
TeamPurple5




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeMhassan,
TeamGreen
2015-04-13 10:48:02 CDT

You could include a short explanation of the evidence provided in the primary annotation used for this gene. How was E. coli Dihydroreducatse activity proven in the paper referenced (ie. proven by direct assay initially).

None, yet.
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Sefa12015-05-04 00:16:15 CDTNo notes given.Acceptable
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Sefa12015-05-04 00:16:13 CDTNo notes given.Acceptable
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Sefa12015-05-04 00:16:12 CDTNo notes given.Acceptable
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Sefa12015-05-04 00:16:12 CDTNo notes given.Acceptable
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Sefa12015-05-04 00:01:46 CDTNo notes given.Acceptable
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Sefa12015-05-04 00:16:09 CDTNo notes given.Acceptable
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DanielRenfro2015-04-22 09:12:02 CDT

This annotation has been flagged because it has been edited since last assessment

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004146 dihydrofolate reductase activity GO_REF:0000100 ISA: Inferred from Sequence Alignment PMID:6815178

UniProtKB:P0ABQ4

F Focused blastp result with e-value 4e-31, query coverage 88%, and identity 41% identifies Escherichia coli str. K-12 dihydrofolate reductase as a homolog for this gene product. Dihydrofolate reductase activity of E. coli K-12 DHFR was found by performing a direct dihydrofolate reductase assay. Conserved residues for the gene product in E. coli (e.g. Ala-7, Phe-31, Leu-54, etc.) had identical residue matches in Troll. complete
CACAO 10866
on 9CAUD:S5Y0G6
Flagged