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Cacao

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GO:0016787hydrolase activityPMID:25462813IDA: Inferred from Direct Assay F
This annotation made on page: HUMAN:EST1
By: Sedmondson (group Team Designated Drinkers) on 2015-02-18 16:26:15 CST.




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Entry TypeChallenging User,GroupTime/DateChallenge ReasonPoints/Assessment
ChallengeJChamblee1995,
Team Ood
2015-03-10 19:50:16 CDT

The GO term should be GO:0052689 (carboxylic ester hydrolase activity) instead of hydrolase activity.

6
ChallengeJChamblee1995,
Team Ood
2015-02-25 20:56:45 CST

I'm going to take back what I said about the go term and say that hydrolase activity is correct. It occurred to me that acetate and acetyl might not actually be the same functional group and when I checked that seems to be the case so what I said in the first challenge on Tuesday, that deacetylase activity was shown, I believe is wrong.

0
ChallengeJChamblee1995,
Team Ood
2015-02-24 19:55:15 CST

-The note is incredibly vague but figure 7 shows CES1 hydrolysis of pNPA. -Also, I believe the term could be more specific and CES1 was actually shown to have deacetylase activity (child term of hydrolase activity, GO:0019213) as it is stated that pNPA (p-nitrophenylacetate) is hydrolyzed and converted to pNP (p-nitrophenol), indicating a loss of an acetate functional group. -Evidence code seems fine

3
Private
Assessment
Amcmillan2015-03-10 20:30:19 CDTYou need to be an instructor to view these notes.Corrected Through Challenges
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original
Public
Assessment
DanielRenfro2015-03-10 19:50:16 CDT

This annotation has been flagged because it has been challenged since last assessment

Flagged
Private
Assessment
Amcmillan2015-03-10 18:41:59 CDTYou need to be an instructor to view these notes.Requires Changes
Go term
Private
Assessment
Suzialeksander2015-03-10 15:36:44 CDTYou need to be an instructor to view these notes.Flagged
Private
Assessment
Suzialeksander2015-03-10 15:35:26 CDTYou need to be an instructor to view these notes.Flagged
Private
Assessment
Suzialeksander2015-03-10 15:29:15 CDTYou need to be an instructor to view these notes.Flagged
Private
Assessment
Suzialeksander2015-03-10 15:27:31 CDTYou need to be an instructor to view these notes.Requires Changes
Protein
Publication
Qualifier
Go term
Evidence
With/From
Notes
Unique/Original