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STRCO:RNC

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Species (Taxon ID) Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145). (100226)
Gene Name(s) rnc (synonyms: absB)
Protein Name(s) Ribonuclease 3

Antibiotic biosynthesis protein B AbsB Ribonuclease III RNase III

External Links
UniProt Q9ZBQ7
EMBL AL939124
PIR T35656
RefSeq NP_629707.1
SMR Q9ZBQ7
STRING 100226.SCO5572
PRIDE Q9ZBQ7
EnsemblBacteria CAA22415
GeneID 1101013
KEGG sco:SCO5572
PATRIC fig|100226.15.peg.5661
eggNOG ENOG4108ZBM
COG0571
HOGENOM HOG000246808
InParanoid Q9ZBQ7
KO K03685
OrthoDB POG091H00R1
BRENDA 3.1.26.3
Proteomes UP000001973
GO GO:0005737
GO:0003725
GO:0046872
GO:0004525
GO:0019843
GO:0006397
GO:0090502
GO:0006396
GO:0016075
GO:0006364
GO:0008033
CDD cd00593
Gene3D 1.10.1520.10
HAMAP MF_00104
InterPro IPR014720
IPR011907
IPR000999
IPR036389
Pfam PF00035
PF14622
SMART SM00358
SM00535
SUPFAM SSF69065
TIGRFAMs TIGR02191
PROSITE PS50137
PS00517
PS50142

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0017000

antibiotic biosynthetic process

PMID:10498729[1]

ECO:0000314

P

Figure 2. shows the PCR primers A and D in the experiment. They were used to make a absB gene template from the wild-type and mutant strains (shown in table 1). The primers were inserted into an E. coli replicon, pBluescript SK(+) (pBK802 to pBK804 and pRK805), in order to be sequences with normal primers and reversed primers. The results of the experiment show that the abs gene encodes the S. coelicolor homolog of RNase III. Also, through a series of processes, absB mutant can be transformed in the wild-type Abs+ when using a gene homologous to the wild-type RNAse III.

complete
CACAO 13183

involved_in

GO:0006396

RNA processing

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10857
PANTHER:PTN000129453

P

Seeded From UniProt

complete

enables

GO:0004525

ribonuclease III activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10857
PANTHER:PTN000129453
PomBase:SPBC119.11c
SGD:S000004852
UniProtKB:Q9NRR4
WB:WBGene00009163

F

Seeded From UniProt

complete

enables

GO:0003725

double-stranded RNA binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000129453
PomBase:SPBC119.11c
TAIR:locus:2024407
UniProtKB:A6YSL1
UniProtKB:Q0IQN6

F

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004519

P

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004518

P

Seeded From UniProt

complete

involved_in

GO:0090501

RNA phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004525

P

Seeded From UniProt

complete

involved_in

GO:0090501

RNA phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004525

P

Seeded From UniProt

complete

involved_in

GO:0090501

RNA phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004525

P

Seeded From UniProt

complete

involved_in

GO:0090501

RNA phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004525

P

Seeded From UniProt

complete

involved_in

GO:0090502

RNA phosphodiester bond hydrolysis, endonucleolytic

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004525

P

Seeded From UniProt

complete

involved_in

GO:0090502

RNA phosphodiester bond hydrolysis, endonucleolytic

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004525

P

Seeded From UniProt

complete

involved_in

GO:0090502

RNA phosphodiester bond hydrolysis, endonucleolytic

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004525

P

Seeded From UniProt

complete

involved_in

GO:0090502

RNA phosphodiester bond hydrolysis, endonucleolytic

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004525

P

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011907

F

Seeded From UniProt

complete

enables

GO:0004525

ribonuclease III activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000999
InterPro:IPR011907
InterPro:IPR036389

F

Seeded From UniProt

complete

involved_in

GO:0006396

RNA processing

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000999
InterPro:IPR036389

P

Seeded From UniProt

complete

involved_in

GO:0016075

rRNA catabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011907

P

Seeded From UniProt

complete

enables

GO:0004525

ribonuclease III activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.26.3

F

Seeded From UniProt

complete

involved_in

GO:0006364

rRNA processing

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000076502

P

Seeded From UniProt

complete

involved_in

GO:0006397

mRNA processing

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000076502

P

Seeded From UniProt

complete

enables

GO:0004525

ribonuclease III activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000076502

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000076502

C

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

complete

enables

GO:0019843

rRNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0699

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0008033

tRNA processing

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0819

P

Seeded From UniProt

complete

involved_in

GO:0006364

rRNA processing

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0698

P

Seeded From UniProt

complete

enables

GO:0004519

endonuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0255

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0004518

nuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0540

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

involved_in

GO:0006397

mRNA processing

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0507

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Price, B et al. (1999) A Streptomyces coelicolor antibiotic regulatory gene, absB, encodes an RNase III homolog. J. Bacteriol. 181 6142-51 PubMed GONUTS page
  2. 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page