GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
STRCL:BLIP
Contents
| Species (Taxon ID) | Streptomyces clavuligerus. (1901) | |
| Gene Name(s) | No Information Provided. | |
| Protein Name(s) | Beta-lactamase inhibitory protein
BLIP | |
| External Links | ||
| UniProt | P35804 | |
| EMBL | M34538 | |
| PIR | A36710 | |
| PDB | 1JTG 1S0W 1XXM 2B5R 2G2U 2G2W 3C4O 3C4P 3C7U 3C7V 3E2K 3E2L 3GMU 3N4I | |
| PDBsum | 1JTG 1S0W 1XXM 2B5R 2G2U 2G2W 3C4O 3C4P 3C7U 3C7V 3E2K 3E2L 3GMU 3N4I | |
| ProteinModelPortal | P35804 | |
| SMR | P35804 | |
| IntAct | P35804 | |
| EvolutionaryTrace | P35804 | |
| GO | GO:0005576 | |
| Gene3D | 3.30.1450.10 | |
| InterPro | IPR009099 IPR024221 | |
| Pfam | PF07467 | |
| PIRSF | PIRSF009292 | |
| SUPFAM | SSF55648 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0033252 |
regulation of beta-lactamase activity |
ECO:0000315 |
P |
Figure 3 shows the interaction between K74G BLIP (a beta-lactamase inhibitory protein mutant) with S. aureus PC1 wild-type β-lactamase and its A104E (beta-lactamase) mutant. K74G BLIP has greater inhibitory effect on the wild type beta-lactamase than the mutant beta-lactamase. Table 2 includes the inhibition constant of the purified K74G BLIP variant for PC1 β-lactamase, which shows about a 10-fold increase in comparison to that of wild type BLIP. |
complete | |||||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Yuan, J et al. (2011) Identification of a β-lactamase inhibitory protein variant that is a potent inhibitor of Staphylococcus PC1 β-lactamase. J. Mol. Biol. 406 730-44 PubMed GONUTS page
