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SCHPO:YPT5
Contents
Species (Taxon ID) | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). (284812) | |
Gene Name(s) | ypt5 | |
Protein Name(s) | GTP-binding protein ypt5 | |
External Links | ||
UniProt | P36586 | |
EMBL | Z22220 CU329670 | |
PIR | A47733 S34729 | |
RefSeq | NP_593907.1 | |
ProteinModelPortal | P36586 | |
SMR | P36586 | |
BioGrid | 278718 | |
STRING | 4896.SPAC6F6.15.1 | |
iPTMnet | P36586 | |
MaxQB | P36586 | |
PaxDb | P36586 | |
PRIDE | P36586 | |
EnsemblFungi | SPAC6F6.15.1 | |
EuPathDB | FungiDB:SPAC6F6.15 | |
PomBase | SPAC6F6.15 | |
HOGENOM | HOG000233968 | |
InParanoid | P36586 | |
OMA | QTTVKFE | |
PhylomeDB | P36586 | |
Reactome | R-SPO-6798695 R-SPO-8854214 R-SPO-8873719 R-SPO-8876198 R-SPO-983231 | |
PRO | PR:P36586 | |
Proteomes | UP000002485 | |
GO | GO:0005829 GO:0031901 GO:0005770 GO:0005634 GO:0005886 GO:0005525 GO:0003924 GO:0006897 GO:0034058 GO:0006886 GO:0006623 GO:0032482 GO:0033157 GO:0007264 | |
InterPro | IPR027417 IPR005225 IPR001806 | |
Pfam | PF00071 | |
SUPFAM | SSF52540 | |
TIGRFAMs | TIGR00231 | |
PROSITE | PS51419 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0031901 |
early endosome membrane |
ECO:0000314 |
C |
figure 9: immunofluorescence microscopy results indicate that ypt5 protein in located in early endosome membrane of transfected HeLa cells. This annotation is IDA because authors' intention is to prove that both proteins (reb5 and ypt5) are homologs and replacing them in HeLa cell line does not affect any phenotype. |
complete | |||||
GO:0034058 |
endosomal vesicle fusion |
ECO:0000315 |
P |
Fig 7: Electron microscopy results indicates that ypt-5 gene disruption results in abnormal vesicle formation (which eventually will bind to endosome and cause abnormal endosome morphology) and disrupted membrane sturcture in mutant Schizosaccharomyces pombe. |
complete | |||||
GO:0034058 |
endosomal vesicle fusion |
ECO:0000315 |
P |
Figure 6: disruption in ypt5 gene (produces protein that regulates vesicle fusion to endosome) disrupts protein function and results in abnormal cell morphology. |
complete | |||||
involved_in |
GO:0034058 |
endosomal vesicle fusion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0031901 |
early endosome membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0033157 |
regulation of intracellular protein transport |
ECO:0000305 |
curator inference used in manual assertion |
GO:0006897 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007264 |
small GTPase mediated signal transduction |
ECO:0000305 |
curator inference used in manual assertion |
GO:0003924 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006897 |
endocytosis |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
SGD:S000001722 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005770 |
late endosome |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
SGD:S000001722 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0005525 |
GTP binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003924 |
GTPase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
SGD:S000001722 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0032482 |
Rab protein signal transduction |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0015790 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006897 |
endocytosis |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002785234 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006886 |
intracellular protein transport |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1914292 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006623 |
protein targeting to vacuole |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002785234 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0003924 |
GTPase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0015790 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0003924 |
GTPase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005525 |
GTP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0015031 |
protein transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005525 |
GTP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Armstrong, J et al. (1993) Schizosaccharomyces pombe ypt5: a homologue of the rab5 endosome fusion regulator. Mol. Biol. Cell 4 583-92 PubMed GONUTS page
- ↑ 2.0 2.1 Matsuyama, A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat. Biotechnol. 24 841-7 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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