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SCHPO:YPT3

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Species (Taxon ID) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). (284812)
Gene Name(s) ypt3 (synonyms: its5)
Protein Name(s) GTP-binding protein ypt3

RAB

External Links
UniProt P17610
EMBL X52100
X52732
CU329670
PIR S10026
RefSeq NP_593667.1
ProteinModelPortal P17610
SMR P17610
BioGrid 278693
MINT MINT-4687464
STRING 4896.SPAC18G6.03-1
MaxQB P17610
PaxDb P17610
PRIDE P17610
EnsemblFungi [example_ID SPAC18G6.03.1]
GeneID 2542219
KEGG spo:SPAC18G6.03
PomBase SPAC18G6.03
eggNOG COG1100
HOGENOM HOG000233968
InParanoid P17610
KO K07904
OMA RTHADPS
OrthoDB EOG7BGHXR
PhylomeDB P17610
NextBio 20803288
GO GO:0005737
GO:0005829
GO:0005768
GO:0005794
GO:0005634
GO:0005886
GO:0005525
GO:0003924
GO:0006887
GO:0071852
GO:0006184
GO:0006886
GO:0000281
GO:0007264
GO:0042144
Gene3D 3.40.50.300
InterPro IPR027417
IPR005225
IPR001806
IPR003579
Pfam PF00071
PRINTS PR00449
SMART SM00175
SUPFAM SSF52540
TIGRFAMs TIGR00231
PROSITE PS51419

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000139

Golgi membrane

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0134

C

Seeded From UniProt

GO:0000166

nucleotide binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

Seeded From UniProt

GO:0003924

GTPase activity

PMID:2328721[1]

ISS: Inferred from Sequence or Structural Similarity

PomBase:SPBC1703.10

F

Seeded From UniProt

GO:0005525

GTP binding

GO_REF:0000001

ISM: Inferred from Sequence Model

Pfam:PF00071

F

Seeded From UniProt

GO:0005525

GTP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001806
InterPro:IPR003579
InterPro:IPR005225

F

Seeded From UniProt

GO:0005525

GTP binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0342

F

Seeded From UniProt

GO:0005634

nucleus

PMID:16823372[2]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0005737

cytoplasm

PMID:12181359[3]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0005768

endosome

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0967

C

Seeded From UniProt

GO:0005794

Golgi apparatus

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0333

C

Seeded From UniProt

GO:0005829

cytosol

PMID:16823372[2]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0005886

plasma membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

Seeded From UniProt

GO:0005886

plasma membrane

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

GO:0006184

GTP catabolic process

PMID:2328721[1]

ISS: Inferred from Sequence or Structural Similarity

PomBase:SPBC1703.10

P

Seeded From UniProt

GO:0006810

transport

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813

P

Seeded From UniProt

GO:0006886

intracellular protein transport

PMID:12181359[3]

TAS: Traceable Author Statement

P

Seeded From UniProt

GO:0006887

exocytosis

PMID:12181359[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0007264

small GTPase mediated signal transduction

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001806
InterPro:IPR003579

P

Seeded From UniProt

GO:0010008

endosome membrane

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0100

C

Seeded From UniProt

GO:0015031

protein transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003579

P

Seeded From UniProt

GO:0015031

protein transport

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0653

P

Seeded From UniProt

GO:0016020

membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

Seeded From UniProt

GO:0033205

cell cycle cytokinesis

PMID:12181359[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0042144

vacuole fusion, non-autophagic

PMID:12181359[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0071852

fungal-type cell wall organization or biogenesis

PMID:12181359[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:1905346

protein localization to cleavage furrow rim

PMID:27082518[4]

IDA: Inferred from Direct Assay

P

Fig. 8 part D's lower right panels details the localization of Ypt3 at the cleavage furrow rim during cytokineses, with red arrows indicating longer docking times than yellow arrows for Ypt3 puncta. The organism is S. pombe, and the authors refer to the protein as Ypt3.

complete
CACAO 12239

GO:0035838

growing cell tip

PMID:27082518[4]

IDA: Inferred from Direct Assay

C

Fig. 8B and 8C details that Ypt3 would travel alone or would colocalize with Ypt2 48% of the time in the punctate structures. This occurred mainly at the cell tip during interphase or at the division site during cytokinesis. Organism is S. pombe. "Indeed, those Ypt3-only puncta also traveled to the division site during cytokinesis and to the growing cell tips during interphase (Fig 8C and S5B Fig, arrows)"

complete
CACAO 12240

GO:0035974

meiotic spindle pole body

PMID:27630265[5]

IDA: Inferred from Direct Assay

C

Figure 6A details Ypt3 localization at the meiotic spindle pole body during sporulation. The organism is S. pombe. The authors refer to the protein as Ypt3 throughout the experiment.

complete
CACAO 12288

GO:0005737

cytoplasm

PMID:27630265[5]

IDA: Inferred from Direct Assay

C

In Fig. 2A GFP-Ypt3 was observed as numerous dots dispersed throughout the cytoplasm during sporulation. The organism is S. pombe, and the authors refer to the gene as Ypt3.

complete
CACAO 12336

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Miyake, S & Yamamoto, M (1990) Identification of ras-related, YPT family genes in Schizosaccharomyces pombe. EMBO J. 9 1417-22 PubMed GONUTS page
  2. 2.0 2.1 Matsuyama, A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat. Biotechnol. 24 841-7 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 Cheng, H et al. (2002) Role of the Rab GTP-binding protein Ypt3 in the fission yeast exocytic pathway and its connection to calcineurin function. Mol. Biol. Cell 13 2963-76 PubMed GONUTS page
  4. 4.0 4.1 Wang, N et al. (2016) Roles of the TRAPP-II Complex and the Exocyst in Membrane Deposition during Fission Yeast Cytokinesis. PLoS Biol. 14 e1002437 PubMed GONUTS page
  5. 5.0 5.1 Imada, K & Nakamura, T (2016) The exocytic Rabs Ypt3 and Ypt2 regulate the early step of biogenesis of the spore plasma membrane in fission yeast. Mol. Biol. Cell 27 3317-3328 PubMed GONUTS page