Have any questions? Please email us at ecoliwiki@gmail.com

SCHPO:VIP1

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Schizosaccharomyces pombe (strain ATCC 38366 / 972) (Fission yeast). (taxon:284812)
Gene Name(s) asp1 ( synonyms: vip1 )
Protein Name(s)
  • Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase
  • Cortical actin cytoskeleton protein asp1
  • InsP6 and PP-IP5 kinase
External Links
UniProt Identifier VIP1_SCHPO
UniProt Accessions O74429,
EMBL CU329672,
PIR T41050,
RefSeq NP_587877.1,
Pfam PF00328, PF08443,

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005856

cytoskeleton

IEA: Inferred from Electronic Annotation

C

Source: UniProtKB-SubCell

GO:0005829

cytosol

IDA: Inferred from Direct Assay

C

Source: GeneDB_Spombe

GO:0005634

nucleus

IDA: Inferred from Direct Assay

C

Source: GeneDB_Spombe

GO:0003993

acid phosphatase activity

IEA: Inferred from Electronic Annotation

F

Source: InterPro

GO:0005524

ATP binding

IEA: Inferred from Electronic Annotation

F

Source: UniProtKB-KW

GO:0033857

diphosphoinositol-pentakisphosphate kinase ...

IEA: Inferred from Electronic Annotation

F

Source: EC

GO:0016301

kinase activity

IEA: Inferred from Electronic Annotation

F

Source: UniProtKB-KW

GO:0030866

cortical actin cytoskeleton organization

IMP: Inferred from Mutant Phenotype

P

Source: GeneDB_Spombe

GO:0043690

cell-cell adhesion involved in flocculation via cell wall protein-carbohydrate interaction

PMID:20624911[1]

IMP: Inferred from Mutant Phenotype

P

Fig. 2, text: "The strain expressing the Asp1 kinase-only variant Asp1H397A flocculated strongly when the cells were grown in rich medium, and this cell-cell adhesion was dependent on the presence of Ca2+ and galactose residues present in cell wall glycoproteins (Fig. 2C; data not shown)."

complete

GO:0030950

establishment or maintenance of actin cytos...

IMP: Inferred from Mutant Phenotype

P

Source: GeneDB_Spombe

GO:0010811

positive regulation of cell-substrate adhesion

PMID:20624911[1]

IMP: Inferred from Mutant Phenotype

P

Figure 3. Asp1 kinase activity is needed for pseudohypha-like invasive growth.

complete

GO:0007124

pseudohyphal growth

PMID:20624911[1]

IMP: Inferred from Mutant Phenotype

P

Figure 3.(B) Photomicrographs of invasively growing colonies show pseudohyphae that grow away from the colony and consist of chains of cells (inset). White bar, 20 um; black bar, 10 um.

complete

GO:0000166

nucleotide binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

GO:0000828

inositol hexakisphosphate kinase activity

GO_REF:0000001

ISS: Inferred from Sequence or Structural Similarity

SGD:S000004402

F

GO:0000832

inositol hexakisphosphate 5-kinase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.7.4.21

F

GO:0003993

acid phosphatase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000560

F

GO:0005524

ATP binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

GO:0005634

nucleus

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0539

C

GO:0005634

nucleus

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0191

C

GO:0005634

nucleus

PMID:16823372[2]

IDA: Inferred from Direct Assay

C

GO:0005737

cytoplasm

GO_REF:0000001

ISS: Inferred from Sequence or Structural Similarity

SGD:S000004402

C

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

GO:0005829

cytosol

PMID:16823372[2]

IDA: Inferred from Direct Assay

C

GO:0005856

cytoskeleton

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0206

C

GO:0005856

cytoskeleton

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0090

C

GO:0016301

kinase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

F

GO:0016310

phosphorylation

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

P

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

GO:0030866

cortical actin cytoskeleton organization

PMID:10388810[3]

IMP: Inferred from Mutant Phenotype

P

GO:0030950

establishment or maintenance of actin cytoskeleton polarity

PMID:10388810[3]

IMP: Inferred from Mutant Phenotype

P

GO:0032958

inositol phosphate biosynthetic process

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

SGD:S000004402

P

GO:0033187

inositol hexakisphosphate 4-kinase or 6-kinase activity

GO_REF:0000001

ISS: Inferred from Sequence or Structural Similarity

SGD:S000004402

F

GO:0033857

diphosphoinositol-pentakisphosphate kinase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.7.4.24

F

GO:0050848

regulation of calcium-mediated signaling

GO_REF:0000001

IC: Inferred by Curator

GO:0033187

P


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Pöhlmann, J & Fleig, U (2010) Asp1, a conserved 1/3 inositol polyphosphate kinase, regulates the dimorphic switch in Schizosaccharomyces pombe. Mol. Cell. Biol. 30 4535-47 PubMed GONUTS page
  2. 2.0 2.1 Matsuyama, A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat. Biotechnol. 24 841-7 PubMed GONUTS page
  3. 3.0 3.1 Feoktistova, A et al. (1999) Identification and characterization of Schizosaccharomyces pombe asp1(+), a gene that interacts with mutations in the Arp2/3 complex and actin. Genetics 152 895-908 PubMed GONUTS page