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SCHPO:SNF1

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Species (Taxon ID) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). (284812)
Gene Name(s) ssp2
Protein Name(s) SNF1-like protein kinase ssp2
External Links
UniProt O74536
EMBL CU329672
PIR T41587
RefSeq NP_588376.1
PDB 2OOX
2OOY
2QR1
2QRC
2QRD
2QRE
3H4J
PDBsum 2OOX
2OOY
2QR1
2QRC
2QRD
2QRE
3H4J
ProteinModelPortal O74536
SMR O74536
BioGrid 275681
DIP DIP-29520N
IntAct O74536
MINT MINT-4679856
iPTMnet O74536
MaxQB O74536
EnsemblFungi SPCC74.03c.1
GeneID 2539109
KEGG spo:SPCC74.03c
EuPathDB FungiDB:SPCC74.03c
PomBase SPCC74.03c
HOGENOM HOG000233016
InParanoid O74536
KO K12761
OMA TIDSNIC
OrthoDB EOG793BK1
PhylomeDB O74536
BRENDA 2.7.11.1
Reactome [www.reactome.org/content/detail/R-SPO-163680 R-SPO-163680]
[www.reactome.org/content/detail/R-SPO-200425 R-SPO-200425]
[www.reactome.org/content/detail/R-SPO-380972 R-SPO-380972]
EvolutionaryTrace O74536
PRO PR:O74536
Proteomes UP000002485
GO GO:0005737
GO:0005829
GO:0044732
GO:0031588
GO:0005634
GO:0005524
GO:0031593
GO:0004672
GO:0004674
GO:2000766
GO:1904262
GO:0006468
GO:0046015
GO:0007165
InterPro IPR032270
IPR028375
IPR011009
IPR000719
IPR017441
IPR008271
IPR015940
IPR013896
Pfam PF16579
PF00069
PF08587
SMART SM00220
SUPFAM SSF103243
SSF56112
PROSITE PS00107
PS50011
PS00108
PS50030

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

Seeded From UniProt

GO:0004672

protein kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR008271

F

Seeded From UniProt

GO:0004672

protein kinase activity

PMID:25639242[1]

IDA: Inferred from Direct Assay

-

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013896

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000678822

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0723

F

Seeded From UniProt

GO:0005515

protein binding

PMID:17289942[2]

IPI: Inferred from Physical Interaction

PomBase:SPCC1919.03c

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR017441

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

Seeded From UniProt

GO:0005634

nucleus

PMID:16823372[3]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0005634

nucleus

PMID:22375066[4]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0005634

nucleus

PMID:22375066[4]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0005737

cytoplasm

PMID:16823372[3]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0005737

cytoplasm

PMID:22375066[4]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0005737

cytoplasm

PMID:22375066[4]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0005737

cytoplasm

PMID:22375066[4]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0005829

cytosol

PMID:16823372[3]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR008271

P

Seeded From UniProt

GO:0016301

kinase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

Seeded From UniProt

GO:0016310

phosphorylation

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

Seeded From UniProt

GO:0016740

transferase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

Seeded From UniProt

GO:0031588

nucleotide-activated protein kinase complex

PMID:17289942[2]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0031593

polyubiquitin binding

PMID:12672455[5]

TAS: Traceable Author Statement

-

F

Seeded From UniProt

GO:0044732

mitotic spindle pole body

PMID:16823372[3]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:1904262

negative regulation of TORC1 signaling

PMID:25639242[1]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0075319

positive regulation of ascus development

PMID:27604537[6]

IMP: Inferred from Mutant Phenotype

P

Figure 1C and 1D

complete
CACAO 12105

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Davie, E et al. (2015) Nitrogen regulates AMPK to control TORC1 signaling. Curr. Biol. 25 445-54 PubMed GONUTS page
  2. 2.0 2.1 Townley, R & Shapiro, L (2007) Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase. Science 315 1726-9 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Matsuyama, A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat. Biotechnol. 24 841-7 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 Valbuena, N & Moreno, S (2012) AMPK phosphorylation by Ssp1 is required for proper sexual differentiation in fission yeast. J. Cell. Sci. 125 2655-64 PubMed GONUTS page
  5. Hartmann-Petersen, R et al. (2003) UBA domain containing proteins in fission yeast. Int. J. Biochem. Cell Biol. 35 629-36 PubMed GONUTS page
  6. Qingyun, et al. (2016) Genetic Interactions among AMPK Catalytic Subunit Ssp2 and Glycogen Synthase Kinases Gsk3 and Gsk31 in Schizosaccharomyces Pombe. Kobe J Med Sci 62 E70-8 PubMed GONUTS page