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SCHPO:SEN1

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Species (Taxon ID) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). (284812)
Gene Name(s) sen1
Protein Name(s) Helicase sen1
External Links
UniProt Q92355
EMBL CU329670
PIR T39072
RefSeq NP_594119.1
ProteinModelPortal Q92355
SMR Q92355
BioGrid 278055
STRING 4896.SPAC6G9.10c.1
iPTMnet Q92355
MaxQB Q92355
PaxDb Q92355
PRIDE Q92355
EnsemblFungi SPAC6G9.10c.1
GeneID 2541556
KEGG spo:SPAC6G9.10c
EuPathDB FungiDB:SPAC6G9.10c
PomBase SPAC6G9.10c
InParanoid Q92355
KO K10706
OMA EYQTEKQ
PhylomeDB Q92355
PRO PR:Q92355
Proteomes UP000002485
GO GO:0000790
GO:0005634
GO:0005657
GO:0035861
GO:0005524
GO:0043141
GO:0033682
GO:0032575
GO:0003723
GO:0045005
GO:0006397
GO:1903623
GO:0006364
GO:0006369
GO:0006283
GO:0008033
InterPro IPR024481
IPR027417
Pfam PF12726
SUPFAM SSF52540

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:1903623

negative regulation of RNA polymerase III activity

PMID:25392932[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

NOT|part_of

GO:0035649

Nrd1 complex

PMID:27401558[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0033682

ATP-dependent 5'-3' DNA/RNA helicase activity

PMID:10545196[3]

ECO:0000314

direct assay evidence used in manual assertion

F

activated_by:(CHEBI:6636)

Seeded From UniProt

complete

enables

GO:0033682

ATP-dependent 5'-3' DNA/RNA helicase activity

PMID:10545196[3]

ECO:0000314

direct assay evidence used in manual assertion

F

activated_by:(CHEBI:63041)

Seeded From UniProt

complete

enables

GO:0032575

ATP-dependent 5'-3' RNA helicase activity

PMID:10545196[3]

ECO:0000314

direct assay evidence used in manual assertion

F

activated_by:(CHEBI:6636)

Seeded From UniProt

complete

enables

GO:0032575

ATP-dependent 5'-3' RNA helicase activity

PMID:10545196[3]

ECO:0000314

direct assay evidence used in manual assertion

F

activated_by:(CHEBI:63041)

Seeded From UniProt

complete

involved_in

GO:0006369

termination of RNA polymerase II transcription

GO_REF:0000024

ECO:0000266

sequence orthology evidence used in manual assertion

SGD:S000004422

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:16823372[4]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0000790

nuclear chromatin

PMID:25392932[1]

ECO:0000314

direct assay evidence used in manual assertion

C

coincident_with:(SO:0001272)

Seeded From UniProt

complete

involved_in

GO:0045005

DNA-dependent DNA replication maintenance of fidelity

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002474780
SGD:S000004422

P

Seeded From UniProt

complete

enables

GO:0043141

ATP-dependent 5'-3' DNA helicase activity

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002474780
SGD:S000004422

F

Seeded From UniProt

complete

part_of

GO:0035861

site of double-strand break

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002474780
PomBase:SPBC29A10.10c

C

Seeded From UniProt

complete

enables

GO:0033682

ATP-dependent 5'-3' DNA/RNA helicase activity

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002474780
PomBase:SPAC6G9.10c
SGD:S000004422

F

Seeded From UniProt

complete

enables

GO:0032575

ATP-dependent 5'-3' RNA helicase activity

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002474780
PomBase:SPAC6G9.10c

F

Seeded From UniProt

complete

involved_in

GO:0008033

tRNA processing

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002474780
SGD:S000004422

P

Seeded From UniProt

complete

involved_in

GO:0006283

transcription-coupled nucleotide-excision repair

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002474780
SGD:S000004422

P

Seeded From UniProt

complete

part_of

GO:0005657

replication fork

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002474780
SGD:S000004422

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002474780
SGD:S000004422

C

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000094509
UniProtKB:Q92900
UniProtKB:Q9HCE1

F

Seeded From UniProt

complete

involved_in

GO:0032508

DNA duplex unwinding

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0043141

P

Seeded From UniProt

complete

enables

GO:0004386

helicase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0347

F

Seeded From UniProt

complete

involved_in

GO:0006364

rRNA processing

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0698

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

involved_in

GO:0006397

mRNA processing

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0507

P

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

involved_in

GO:0008033

tRNA processing

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0819

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

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Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 Legros, P et al. (2014) RNA processing factors Swd2.2 and Sen1 antagonize RNA Pol III-dependent transcription and the localization of condensin at Pol III genes. PLoS Genet. 10 e1004794 PubMed GONUTS page
  2. ↑ Lemay, JF et al. (2016) The Nrd1-like protein Seb1 coordinates cotranscriptional 3' end processing and polyadenylation site selection. Genes Dev. 30 1558-72 PubMed GONUTS page
  3. ↑ 3.0 3.1 3.2 3.3 Kim, HD et al. (1999) The sen1(+) gene of Schizosaccharomyces pombe, a homologue of budding yeast SEN1, encodes an RNA and DNA helicase. Biochemistry 38 14697-710 PubMed GONUTS page
  4. ↑ Matsuyama, A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat. Biotechnol. 24 841-7 PubMed GONUTS page
  5. ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 5.7 5.8 5.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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