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SCHPO:RNA14

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Species (Taxon ID) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). (284812)
Gene Name(s) rna14
Protein Name(s) mRNA 3'-end-processing protein rna14
External Links
UniProt O14233
EMBL CU329670
PIR T11668
RefSeq NP_593303.1
ProteinModelPortal O14233
BioGrid 278097
STRING 4896.SPAC6F12.17.1
iPTMnet O14233
MaxQB O14233
PaxDb O14233
PRIDE O14233
EnsemblFungi SPAC6F12.17.1
GeneID 2541600
KEGG spo:SPAC6F12.17
EuPathDB FungiDB:SPAC6F12.17
PomBase SPAC6F12.17
InParanoid O14233
KO K14408
OMA NICIAQL
PhylomeDB O14233
PRO PR:O14233
Proteomes UP000002485
GO GO:0005739
GO:0005847
GO:0005634
GO:0003729
GO:0006379
GO:0006378
GO:0031440
GO:0031123
InterPro IPR003107
IPR008847
IPR011990
Pfam PF05843
SMART SM00386
SUPFAM SSF48452

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0051984

positive regulation of chromosome segregation

PMID:26581324[1]

ECO:0000315

P

Fig. 2 part C shows chromosome segregation defects indicated by arrows in the Rna14 mutant. Fig. 3 part B shows the percentage of chromosome loss over time in both the wild type and mutant Rna14 strains, and indicates a 20% chromosome loss with the Rna14 mutant after twelve hours. Fig. 3 part C shows the timed viability of these Rn14 mutants, with only 10% of the Rna14 mutants surviving after 12 hours. These show Rna14 having a positive regulation of chromosome segregation in the organism S. pombe. Both the experiment and UniProt refer to the gene as Rna14.

complete
CACAO 12511

involved_in

GO:0031440

regulation of mRNA 3'-end processing

PMID:26581324[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006379

mRNA cleavage

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P25298

P

Seeded From UniProt

complete

involved_in

GO:0006378

mRNA polyadenylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P25298

P

Seeded From UniProt

complete

part_of

GO:0005847

mRNA cleavage and polyadenylation specificity factor complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P25298

C

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P25298

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:16823372[2]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:26581324[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003674

molecular_function

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0031123

RNA 3'-end processing

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000463331
TAIR:locus:2007973

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000463331
PomBase:SPAC6F12.17
SGD:S000004665

C

Seeded From UniProt

complete

enables

GO:0003729

mRNA binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000463331
TAIR:locus:2007973

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008847

C

Seeded From UniProt

complete

involved_in

GO:0006396

RNA processing

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003107

P

Seeded From UniProt

complete

involved_in

GO:0006397

mRNA processing

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008847

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0006397

mRNA processing

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0507

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Sonkar, A et al. (2016) Cleavage and polyadenylation factor, Rna14 is an essential protein required for the maintenance of genomic integrity in fission yeast Schizosaccharomyces pombe. Biochim. Biophys. Acta 1863 189-97 PubMed GONUTS page
  2. Matsuyama, A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat. Biotechnol. 24 841-7 PubMed GONUTS page
  3. 3.0 3.1 3.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page