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SCHPO:PDC1

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Species (Taxon ID) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). (284812)
Gene Name(s) No Information Provided.
Protein Name(s) Putative pyruvate decarboxylase C13A11.06
External Links
UniProt Q09737
EMBL CU329670
PIR T38759
RefSeq XP_001713041.1
ProteinModelPortal Q09737
STRING Q09737
EnsemblFungi SPAC13A11.06.1
GeneID 3361478
KEGG spo:SPAC13A11.06
PomBase SPAC13A11.06
eggNOG COG3961
HOGENOM HOG000061334
KO K01568
OMA ACAIRHR
OrthoDB EOG41NXVF
NextBio 20811521
GO GO:0005829
GO:0005634
GO:0000287
GO:0004737
GO:0030976
GO:0000949
GO:0019655
GO:0006090
InterPro IPR012000
IPR012001
IPR012110
IPR011766
PANTHER PTHR18968:SF4
Pfam PF02775
PF00205
PF02776
PIRSF PIRSF036565
PROSITE PS00187

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000287

magnesium ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR012000

F

Seeded From UniProt

GO:0000949

aromatic amino acid family catabolic process to alcohol via Ehrlich pathway

GO_REF:0000024

ISO: Inferred from Sequence Orthology

SGD:S000004124

P

Seeded From UniProt

GO:0003824

catalytic activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011766

F

Seeded From UniProt

GO:0004737

pyruvate decarboxylase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:4.1.1.1

F

Seeded From UniProt

GO:0004737

pyruvate decarboxylase activity

GO_REF:0000024

ISO: Inferred from Sequence Orthology

SGD:S000003319

F

Seeded From UniProt

GO:0005634

nucleus

PMID:16823372[1]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0005829

cytosol

PMID:16823372[1]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0006090

pyruvate metabolic process

GO_REF:0000024

ISO: Inferred from Sequence Orthology

SGD:S000004124

P

Seeded From UniProt

GO:0016829

lyase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0456

F

Seeded From UniProt

GO:0016831

carboxy-lyase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0210

F

Seeded From UniProt

GO:0019655

glucose catabolic process to ethanol

GO_REF:0000024

ISO: Inferred from Sequence Orthology

SGD:S000004124

P

Seeded From UniProt

GO:0030976

thiamine pyrophosphate binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011766
InterPro:IPR012000
InterPro:IPR012001

F

Seeded From UniProt

GO:0046872

metal ion binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

Seeded From UniProt

GO:0033962

cytoplasmic mRNA processing body assembly

PMID:23319050[2]

IMP: Inferred from Mutant Phenotype

P

Figure 5 demonstrates the requirement of pdc1 in p-body assembly and Figure 6 shows the "scaffolding" region of the protein for p-body assembly.

complete
CACAO 7236

GO:1901835

positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA

PMID:23319050[2]

IMP: Inferred from Mutant Phenotype

P

Figure 7 B and C shows the lack of mRNA decapping in pdc1 mutants and enhanced decapping activity when overexpressed as compared to the wild-type.

complete
CACAO 7237

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Matsuyama, A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat. Biotechnol. 24 841-7 PubMed GONUTS page
  2. 2.0 2.1 Wang, CY et al. (2013) Pdc1 functions in the assembly of P bodies in Schizosaccharomyces pombe. Mol. Cell. Biol. 33 1244-53 PubMed GONUTS page