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SCHPO:DSK1

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Species (Taxon ID) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). (284812)
Gene Name(s) dsk1
Protein Name(s) Protein kinase dsk1

Dis1-suppressing protein kinase

External Links
UniProt P36616
EMBL D13447
CU329671
PIR A47726
RefSeq NP_595327.1
ProteinModelPortal P36616
BioGrid 276395
MINT MINT-4689045
MaxQB P36616
EnsemblFungi [example_ID SPBC530.14c.1]
GeneID 2539847
KEGG spo:SPBC530.14c
EuPathDB FungiDB:SPBC530.14c
PomBase SPBC530.14c
HOGENOM HOG000171558
InParanoid P36616
KO K08832
OMA DAEDKKC
OrthoDB EOG7SV148
PhylomeDB P36616
BRENDA 2.7.11.1
NextBio 20800994
PRO PR:P36616
Proteomes UP000002485
GO GO:0032153
GO:0005737
GO:0005829
GO:0044732
GO:0005634
GO:0005524
GO:0004672
GO:0004674
GO:0050265
GO:0051301
GO:0035556
GO:0007067
GO:1900181
GO:0048026
GO:1900182
GO:0046777
GO:0006468
GO:0046822
InterPro IPR011009
IPR000719
IPR017441
IPR008271
Pfam PF00069
SUPFAM SSF56112
PROSITE PS00107
PS50011
PS00108

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

Seeded From UniProt

GO:0004672

protein kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR008271

F

Seeded From UniProt

GO:0004672

protein kinase activity

PMID:12186627[1]

IDA: Inferred from Direct Assay

-

F

Seeded From UniProt

GO:0004672

protein kinase activity

PMID:12186627[1]

IDA: Inferred from Direct Assay

-

F

Seeded From UniProt

GO:0004672

protein kinase activity

PMID:9488736[2]

IDA: Inferred from Direct Assay

-

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0723

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

PMID:10629038[3]

IDA: Inferred from Direct Assay

-

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

PMID:10629038[3]

IDA: Inferred from Direct Assay

-

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

PMID:10629038[3]

IDA: Inferred from Direct Assay

-

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

PMID:8485317[4]

IDA: Inferred from Direct Assay

-

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

PMID:8485317[4]

IDA: Inferred from Direct Assay

-

F

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

PMID:9488736[2]

IDA: Inferred from Direct Assay

-

F

Seeded From UniProt

GO:0005515

protein binding

PMID:10629038[3]

IPI: Inferred from Physical Interaction

PomBase:SPAC16.02c

F

Seeded From UniProt

GO:0005515

protein binding

PMID:10629038[3]

IPI: Inferred from Physical Interaction

PomBase:SPBC11C11.08

F

Seeded From UniProt

GO:0005515

protein binding

PMID:10629038[3]

IPI: Inferred from Physical Interaction

PomBase:SPBC146.07

F

Seeded From UniProt

GO:0005515

protein binding

PMID:9488736[2]

IPI: Inferred from Physical Interaction

PomBase:SPBC146.07

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR017441

F

Seeded From UniProt

GO:0005524

ATP binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

Seeded From UniProt

GO:0005634

nucleus

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

Seeded From UniProt

GO:0005634

nucleus

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

GO:0005634

nucleus

PMID:16823372[5]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0005634

nucleus

PMID:22683458[6]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0005634

nucleus

PMID:8485317[4]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

GO:0005737

cytoplasm

PMID:8485317[4]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0005829

cytosol

PMID:16823372[5]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR008271

P

Seeded From UniProt

GO:0006468

protein phosphorylation

PMID:12186627[1]

IDA: Inferred from Direct Assay

-

P

Seeded From UniProt

GO:0007049

cell cycle

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0131

P

Seeded From UniProt

GO:0007067

mitotic nuclear division

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0498

P

Seeded From UniProt

GO:0016301

kinase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

Seeded From UniProt

GO:0016310

phosphorylation

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

Seeded From UniProt

GO:0016740

transferase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

Seeded From UniProt

GO:0032153

cell division site

PMID:16823372[5]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0035556

intracellular signal transduction

GO_REF:0000001

NAS: Non-traceable Author Statement

-

P

Seeded From UniProt

GO:0044732

mitotic spindle pole body

PMID:16823372[5]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0046777

protein autophosphorylation

PMID:9488736[2]

IDA: Inferred from Direct Assay

-

P

Seeded From UniProt

GO:0046822

regulation of nucleocytoplasmic transport

PMID:17362205[7]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0048026

positive regulation of mRNA splicing, via spliceosome

PMID:21745468[8]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0050265

RNA uridylyltransferase activity

PMID:22683458[6]

IDA: Inferred from Direct Assay

-

F

Seeded From UniProt

GO:0051301

cell division

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0132

P

Seeded From UniProt

GO:1900181

negative regulation of protein localization to nucleus

PMID:17362205[7]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:1900182

positive regulation of protein localization to nucleus

PMID:17362205[7]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:1900182

positive regulation of protein localization to nucleus

PMID:17362205[7]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0004674

protein serine/threonine kinase activity

PMID:26167880[9]

IGI: Inferred from Genetic Interaction

UniProtKB:O74555


F

Figure 5a shows Bpb1 being phosphorylated by dsk1 in a western blot.

complete
CACAO 11250

GO:0018105

peptidyl-serine phosphorylation

PMID:26167880[9]

IGI: Inferred from Genetic Interaction

UniProtKB:O74555


P

Figure 5a shows Bpb1 being phosphorylated by dsk1 in a western blot.

complete
CACAO 11266

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Tang, Z et al. (2002) Interactions between two fission yeast serine/arginine-rich proteins and their modulation by phosphorylation. Biochem. J. 368 527-34 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Tang, Z et al. (1998) Fission yeast mitotic regulator Dsk1 is an SR protein-specific kinase. J. Biol. Chem. 273 5963-9 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 Tang, Z et al. (2000) Biochemical and genetic conservation of fission yeast Dsk1 and human SR protein-specific kinase 1. Mol. Cell. Biol. 20 816-24 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Takeuchi, M & Yanagida, M (1993) A mitotic role for a novel fission yeast protein kinase dsk1 with cell cycle stage dependent phosphorylation and localization. Mol. Biol. Cell 4 247-60 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 Matsuyama, A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat. Biotechnol. 24 841-7 PubMed GONUTS page
  6. 6.0 6.1 Tang, Z et al. (2012) Interacting factors and cellular localization of SR protein-specific kinase Dsk1. Exp. Cell Res. 318 2071-84 PubMed GONUTS page
  7. 7.0 7.1 7.2 7.3 Tang, Z et al. (2007) Dsk1p kinase phosphorylates SR proteins and regulates their cellular localization in fission yeast. Biochem. J. 405 21-30 PubMed GONUTS page
  8. Tang, Z et al. (2011) LAMMER kinase Kic1 is involved in pre-mRNA processing. Exp. Cell Res. 317 2308-20 PubMed GONUTS page
  9. 9.0 9.1 Lipp, JJ et al. (2015) SR protein kinases promote splicing of nonconsensus introns. Nat. Struct. Mol. Biol. 22 611-7 PubMed GONUTS page