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SCHPO:CSK2B

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Species (Taxon ID) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). (284812)
Gene Name(s) ckb1
Protein Name(s) Casein kinase II subunit beta

CK II beta

External Links
UniProt P40232
EMBL X74274
CU329670
PIR T50126
RefSeq NP_594606.1
ProteinModelPortal P40232
SMR P40232
BioGrid 279020
MINT MINT-4689450
MaxQB P40232
EnsemblFungi [example_ID SPAC1851.03.1]
GeneID 2542564
KEGG spo:SPAC1851.03
EuPathDB FungiDB:SPAC1851.03
PomBase SPAC1851.03
HOGENOM HOG000039270
InParanoid P40232
KO K03115
OMA DTIPKRI
OrthoDB EOG7K6Q6G
PhylomeDB P40232
Reactome R-SPO-2514853
NextBio 20803615
PRO PR:P40232
Proteomes UP000002485
GO GO:0044732
GO:0005634
GO:0005956
GO:0034456
GO:0030291
GO:0071901
GO:0006356
GO:0006359
GO:0007165
Gene3D 1.10.1820.10
2.20.25.20
InterPro IPR016149
IPR016150
IPR000704
PANTHER PTHR11740
Pfam PF01214
PRINTS PR00472
SMART SM01085
SUPFAM SSF57798
PROSITE PS01101

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005634

nucleus

PMID:16823372[1]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0005956

protein kinase CK2 complex

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000704
InterPro:IPR016149
InterPro:IPR016150

C

Seeded From UniProt

GO:0005956

protein kinase CK2 complex

GO_REF:0000024

ISO: Inferred from Sequence Orthology

SGD:S000005565

C

Seeded From UniProt

GO:0006356

regulation of transcription from RNA polymerase I promoter

GO_REF:0000024

ISO: Inferred from Sequence Orthology

SGD:S000005565

P

Seeded From UniProt

GO:0006359

regulation of transcription from RNA polymerase III promoter

GO_REF:0000024

ISO: Inferred from Sequence Orthology

SGD:S000005565

P

Seeded From UniProt

GO:0007165

signal transduction

GO_REF:0000001

IC: Inferred by Curator

GO:0019887

P

Seeded From UniProt

GO:0019887

protein kinase regulator activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000704
InterPro:IPR016149
InterPro:IPR016150

F

Seeded From UniProt

GO:0030291

protein serine/threonine kinase inhibitor activity

GO_REF:0000024

ISO: Inferred from Sequence Orthology

SGD:S000005565

F

Seeded From UniProt

GO:0034456

UTP-C complex

GO_REF:0000024

ISO: Inferred from Sequence Orthology

SGD:S000005565

C

Seeded From UniProt

GO:0044732

mitotic spindle pole body

PMID:16823372[1]

IDA: Inferred from Direct Assay

-

C

Seeded From UniProt

GO:0045859

regulation of protein kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000704
InterPro:IPR016149
InterPro:IPR016150

P

Seeded From UniProt

GO:0071901

negative regulation of protein serine/threonine kinase activity

GO_REF:0000024

ISO: Inferred from Sequence Orthology

SGD:S000005565

P

Seeded From UniProt

GO:0090053

positive regulation of chromatin silencing at centromere

PMID:19136623[2]

IMP: Inferred from Mutant Phenotype

P

disruption of ckb1 alleviated the silencing of marker genes inserted in centromeric heterochromatin (Fig. 1B)

complete
CACAO 11285

GO:0006468

protein phosphorylation

PMID:19136623[2]

IMP: Inferred from Mutant Phenotype

P

Figure 2 Since Ckb1 is a regulatory subunit of casein kinase II (CK2) CK2 phosphorylates Swi6

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Matsuyama, A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat. Biotechnol. 24 841-7 PubMed GONUTS page
  2. 2.0 2.1 Shimada, A et al. (2009) Phosphorylation of Swi6/HP1 regulates transcriptional gene silencing at heterochromatin. Genes Dev. 23 18-23 PubMed GONUTS page