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SCHPO:CALX

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Species (Taxon ID) Schizosaccharomyces pombe (strain ATCC 38366 / 972) (Fission yeast). (taxon:284812)
Gene Name(s) cal1 ( synonyms: cnx1 )
Protein Name(s)
  • Calnexin homolog
External Links
UniProt Identifier CALX_SCHPO
UniProt Accessions P36581,
EMBL M98799, U13389, CU329670,
PIR S56142,
RefSeq NP_593612.1,
Pfam PF00262,

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005789

endoplasmic reticulum membrane

TAS: Traceable Author Statement

C

Source: GeneDB_Spombe

GO:0016021

integral to membrane

IEA: Inferred from Electronic Annotation

C

Source: UniProtKB-KW

GO:0005509

calcium ion binding

TAS: Traceable Author Statement

F

Source: GeneDB_Spombe

GO:0005529

sugar binding

IEA: Inferred from Electronic Annotation

F

Source: UniProtKB-KW

GO:0051082

unfolded protein binding

IEA: Inferred from Electronic Annotation

F

Source: InterPro

GO:0006915

apoptosis

IMP: Inferred from Mutant Phenotype

P

Source: GeneDB_Spombe

GO:0034605

cellular response to heat

TAS: Traceable Author Statement

P

Source: GeneDB_Spombe

GO:0006515

misfolded or incompletely synthesized prote...

IMP: Inferred from Mutant Phenotype

P

Source: GeneDB_Spombe

GO:0034975

protein folding in endoplasmic reticulum

IDA: Inferred from Direct Assay

P

Source: GeneDB_Spombe

NOT

GO:0040007

growth

PMID:19351719[1]

IMP: Inferred from Mutant Phenotype

P

Fig. 3. cif1+ is unessential for vegetative growth.

complete

GO:0005509

calcium ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001580

F

GO:0005509

calcium ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009033

F

GO:0005509

calcium ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR018124

F

GO:0005509

calcium ion binding

PMID:7621821[2]

TAS: Traceable Author Statement

F

GO:0005515

protein binding

PMID:9860839[3]

IPI: Inferred from Physical Interaction

GeneDB_Spombe:SPAC22A12.15c

F

GO:0005529

sugar binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0430

F

GO:0005783

endoplasmic reticulum

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009033

C

GO:0005783

endoplasmic reticulum

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0256

C

GO:0005783

endoplasmic reticulum

PMID:16823372[4]

IDA: Inferred from Direct Assay

C

GO:0005789

endoplasmic reticulum membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0097

C

GO:0005789

endoplasmic reticulum membrane

PMID:7621821[2]

TAS: Traceable Author Statement

C

GO:0006457

protein folding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009033

P

GO:0006515

misfolded or incompletely synthesized protein catabolic process

PMID:9860839[3]

IMP: Inferred from Mutant Phenotype

P

GO:0006915

apoptosis

PMID:18701708[5]

IMP: Inferred from Mutant Phenotype

P

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

GO:0030433

ER-associated protein catabolic process

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

SGD:S000000054

P

GO:0034605

cellular response to heat

PMID:7621821[2]

TAS: Traceable Author Statement

P

GO:0034975

protein folding in endoplasmic reticulum

PMID:9860839[3]

IDA: Inferred from Direct Assay

P

GO:0051082

unfolded protein binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009033

F


Notes

References

See Help:References for how to manage references in GONUTS.

  1. Beauregard, PB et al. (2009) A nucleolar protein allows viability in the absence of the essential ER-residing molecular chaperone calnexin. J. Cell. Sci. 122 1342-51 PubMed GONUTS page
  2. 2.0 2.1 2.2 Parlati, F et al. (1995) The calnexin homologue cnx1+ in Schizosaccharomyces pombe, is an essential gene which can be complemented by its soluble ER domain. EMBO J. 14 3064-72 PubMed GONUTS page
  3. 3.0 3.1 3.2 Jannatipour, M et al. (1998) Calnexin and BiP interact with acid phosphatase independently of glucose trimming and reglucosylation in Schizosaccharomyces pombe. Biochemistry 37 17253-61 PubMed GONUTS page
  4. Matsuyama, A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat. Biotechnol. 24 841-7 PubMed GONUTS page
  5. Guérin, R et al. (2008) Calnexin is involved in apoptosis induced by endoplasmic reticulum stress in the fission yeast. Mol. Biol. Cell 19 4404-20 PubMed GONUTS page