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SCHPO:CALX
Contents
| Species (Taxon ID) | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). (284812) | |
| Gene Name(s) | cal1 (synonyms: cnx1) | |
| Protein Name(s) | Calnexin homolog | |
| External Links | ||
| UniProt | P36581 | |
| EMBL | M98799 U13389 CU329670 | |
| PIR | S56142 | |
| RefSeq | NP_593612.1 | |
| ProteinModelPortal | P36581 | |
| BioGrid | 279476 | |
| STRING | 4896.SPAC3C7.11c.1 | |
| iPTMnet | P36581 | |
| MaxQB | P36581 | |
| PaxDb | P36581 | |
| PRIDE | P36581 | |
| EnsemblFungi | SPAC3C7.11c.1 | |
| EuPathDB | FungiDB:SPAC3C7.11c | |
| PomBase | SPAC3C7.11c | |
| HOGENOM | HOG000192435 | |
| InParanoid | P36581 | |
| OMA | FCCSGKK | |
| PhylomeDB | P36581 | |
| Reactome | R-SPO-901042 | |
| PRO | PR:P36581 | |
| Proteomes | UP000002485 | |
| GO | GO:0005783 GO:0005789 GO:0000324 GO:0016021 GO:0005509 GO:0030246 GO:0051082 GO:0006915 GO:0006457 GO:0030433 | |
| Gene3D | 2.10.250.10 | |
| InterPro | IPR001580 IPR018124 IPR009033 IPR013320 | |
| PANTHER | PTHR11073 | |
| Pfam | PF00262 | |
| PRINTS | PR00626 | |
| SUPFAM | SSF49899 SSF63887 | |
| PROSITE | PS00803 PS00804 PS00805 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005789 |
endoplasmic reticulum membrane |
ECO:0000304 |
C |
Source: GeneDB_Spombe |
Missing: reference | |||||
| GO:0005509 |
calcium ion binding |
ECO:0000304 |
F |
Source: GeneDB_Spombe |
Missing: reference | |||||
| GO:0006915 |
apoptosis |
ECO:0000315 |
P |
Source: GeneDB_Spombe |
Missing: reference | |||||
| GO:0034605 |
cellular response to heat |
ECO:0000304 |
P |
Source: GeneDB_Spombe |
Missing: reference | |||||
| GO:0006515 |
misfolded or incompletely synthesized prote... |
ECO:0000315 |
P |
Source: GeneDB_Spombe |
Missing: reference | |||||
| GO:0034975 |
protein folding in endoplasmic reticulum |
ECO:0000314 |
P |
Source: GeneDB_Spombe |
Missing: reference | |||||
|
NOT |
GO:0040007 |
growth |
ECO:0000315 |
P |
Fig. 3. cif1+ is unessential for vegetative growth. |
complete | ||||
|
involved_in |
GO:0030433 |
ubiquitin-dependent ERAD pathway |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
SGD:S000000054 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
| GO:0005509 |
calcium ion binding |
ECO:0000304 |
F |
complete | ||||||
|
involved_in |
GO:0006915 |
apoptotic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
| GO:0005515 |
protein binding |
ECO:0000021 |
GeneDB_Spombe:SPAC22A12.15c |
F |
complete | |||||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
exists_during:(GO:0072690) |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005509 |
calcium ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000324 |
fungal-type vacuole |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
exists_during:(GO:0006995) |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005509 |
calcium ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006457 |
protein folding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
| GO:0006515 |
misfolded or incompletely synthesized protein catabolic process |
ECO:0000315 |
P |
complete | ||||||
|
enables |
GO:0051082 |
unfolded protein binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
| GO:0006915 |
apoptosis |
ECO:0000315 |
P |
complete | ||||||
|
part_of |
GO:0005789 |
endoplasmic reticulum membrane |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0030246 |
carbohydrate binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
| GO:0030433 |
ER-associated protein catabolic process |
ECO:0000250 |
SGD:S000000054 |
P |
complete | |||||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005789 |
endoplasmic reticulum membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Beauregard, PB et al. (2009) A nucleolar protein allows viability in the absence of the essential ER-residing molecular chaperone calnexin. J. Cell. Sci. 122 1342-51 PubMed GONUTS page
- ↑ Jannatipour, M & Rokeach, LA (1995) The Schizosaccharomyces pombe homologue of the chaperone calnexin is essential for viability. J. Biol. Chem. 270 4845-53 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Parlati, F et al. (1995) The calnexin homologue cnx1+ in Schizosaccharomyces pombe, is an essential gene which can be complemented by its soluble ER domain. EMBO J. 14 3064-72 PubMed GONUTS page
- ↑ 4.0 4.1 Guérin, R et al. (2008) Calnexin is involved in apoptosis induced by endoplasmic reticulum stress in the fission yeast. Mol. Biol. Cell 19 4404-20 PubMed GONUTS page
- ↑ 5.0 5.1 Jannatipour, M et al. (1998) Calnexin and BiP interact with acid phosphatase independently of glucose trimming and reglucosylation in Schizosaccharomyces pombe. Biochemistry 37 17253-61 PubMed GONUTS page
- ↑ Matsuyama, A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat. Biotechnol. 24 841-7 PubMed GONUTS page
- ↑ 7.0 7.1 Núñez, A et al. (2015) Calnexin is essential for survival under nitrogen starvation and stationary phase in Schizosaccharomyces pombe. PLoS ONE 10 e0121059 PubMed GONUTS page
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