It is now the 2nd CHALLENGE Period for CACAO Spring 2018! It will end on Monday February 26, 2018 at 05:59 pm CST
This is your chance to challenge other team's annotations. You may also DEFEND or suggest improvements to your own annotations IF they have been challenged. Please note, although we ENCOURAGE challenges, an excess of identical challenges that do not appear to be applicable to the annotation or well thought out will be considered spam and ignored.

Have any questions? Please email us at ecoliwiki@gmail.com

SCHPO:CALX

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Schizosaccharomyces pombe (strain ATCC 38366 / 972) (Fission yeast). (taxon:284812)
Gene Name(s) cal1 ( synonyms: cnx1 )
Protein Name(s)
  • Calnexin homolog
External Links
UniProt Identifier CALX_SCHPO
UniProt Accessions P36581,
EMBL M98799, U13389, CU329670,
PIR S56142,
RefSeq NP_593612.1,
Pfam PF00262,

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005789

endoplasmic reticulum membrane

TAS: Traceable Author Statement

C

Source: GeneDB_Spombe

GO:0016021

integral to membrane

IEA: Inferred from Electronic Annotation

C

Source: UniProtKB-KW

GO:0005509

calcium ion binding

TAS: Traceable Author Statement

F

Source: GeneDB_Spombe

GO:0005529

sugar binding

IEA: Inferred from Electronic Annotation

F

Source: UniProtKB-KW

GO:0051082

unfolded protein binding

IEA: Inferred from Electronic Annotation

F

Source: InterPro

GO:0006915

apoptosis

IMP: Inferred from Mutant Phenotype

P

Source: GeneDB_Spombe

GO:0034605

cellular response to heat

TAS: Traceable Author Statement

P

Source: GeneDB_Spombe

GO:0006515

misfolded or incompletely synthesized prote...

IMP: Inferred from Mutant Phenotype

P

Source: GeneDB_Spombe

GO:0034975

protein folding in endoplasmic reticulum

IDA: Inferred from Direct Assay

P

Source: GeneDB_Spombe

NOT

GO:0040007

growth

PMID:19351719[1]

IMP: Inferred from Mutant Phenotype

P

Fig. 3. cif1+ is unessential for vegetative growth.

complete

GO:0005509

calcium ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001580

F

GO:0005509

calcium ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009033

F

GO:0005509

calcium ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR018124

F

GO:0005509

calcium ion binding

PMID:7621821[2]

TAS: Traceable Author Statement

F

GO:0005515

protein binding

PMID:9860839[3]

IPI: Inferred from Physical Interaction

GeneDB_Spombe:SPAC22A12.15c

F

GO:0005529

sugar binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0430

F

GO:0005783

endoplasmic reticulum

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009033

C

GO:0005783

endoplasmic reticulum

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0256

C

GO:0005783

endoplasmic reticulum

PMID:16823372[4]

IDA: Inferred from Direct Assay

C

GO:0005789

endoplasmic reticulum membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0097

C

GO:0005789

endoplasmic reticulum membrane

PMID:7621821[2]

TAS: Traceable Author Statement

C

GO:0006457

protein folding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009033

P

GO:0006515

misfolded or incompletely synthesized protein catabolic process

PMID:9860839[3]

IMP: Inferred from Mutant Phenotype

P

GO:0006915

apoptosis

PMID:18701708[5]

IMP: Inferred from Mutant Phenotype

P

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

GO:0016021

integral to membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

GO:0030433

ER-associated protein catabolic process

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

SGD:S000000054

P

GO:0034605

cellular response to heat

PMID:7621821[2]

TAS: Traceable Author Statement

P

GO:0034975

protein folding in endoplasmic reticulum

PMID:9860839[3]

IDA: Inferred from Direct Assay

P

GO:0051082

unfolded protein binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR009033

F


Notes

References

See Help:References for how to manage references in GONUTS.

  1. Beauregard, PB et al. (2009) A nucleolar protein allows viability in the absence of the essential ER-residing molecular chaperone calnexin. J. Cell. Sci. 122 1342-51 PubMed GONUTS page
  2. 2.0 2.1 2.2 Parlati, F et al. (1995) The calnexin homologue cnx1+ in Schizosaccharomyces pombe, is an essential gene which can be complemented by its soluble ER domain. EMBO J. 14 3064-72 PubMed GONUTS page
  3. 3.0 3.1 3.2 Jannatipour, M et al. (1998) Calnexin and BiP interact with acid phosphatase independently of glucose trimming and reglucosylation in Schizosaccharomyces pombe. Biochemistry 37 17253-61 PubMed GONUTS page
  4. Matsuyama, A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat. Biotechnol. 24 841-7 PubMed GONUTS page
  5. Guérin, R et al. (2008) Calnexin is involved in apoptosis induced by endoplasmic reticulum stress in the fission yeast. Mol. Biol. Cell 19 4404-20 PubMed GONUTS page