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SCHPO:ATF1

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Species (Taxon ID) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). (284812)
Gene Name(s) atf1 (synonyms: gad7, mts1, sss1)
Protein Name(s) Transcription factor atf1

Protein sss1 Transcription factor mts1

External Links
UniProt P52890
EMBL D63762
U38237
U87869
D63666
D83992
CU329671
PIR S66147
RefSeq NP_595652.1
ProteinModelPortal P52890
BioGrid 276859
IntAct P52890
MINT MINT-4690852
STRING 4896.SPBC29B5.01-1
EnsemblFungi [example_ID SPBC29B5.01.1]
GeneID 2540329
KEGG spo:SPBC29B5.01
PomBase SPBC29B5.01
eggNOG NOG306955
KO K09051
OrthoDB EOG7M0P25
PhylomeDB P52890
NextBio 20801458
GO GO:1990243
GO:0000790
GO:0005634
GO:0046982
GO:0042803
GO:0010844
GO:0003723
GO:0000978
GO:0000982
GO:0001077
GO:0043565
GO:0010846
GO:0070301
GO:0006995
GO:0009267
GO:0007126
GO:0031990
GO:0045128
GO:0036129
GO:0045944
GO:0045893
GO:0043949
GO:0010847
GO:0010848
GO:1900411
GO:1900412
GO:0010520
GO:0006366
InterPro IPR004827
IPR021755
IPR021756
IPR020956
Pfam PF11786
PF11787
PF11785
PF00170
SMART SM00338
PROSITE PS50217

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000080

mitotic G1 phase

PMID:9135083[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0000790

nuclear chromatin

GO_REF:0000001

NAS: Non-traceable Author Statement

C

Seeded From UniProt

GO:0000978

RNA polymerase II core promoter proximal region sequence-specific DNA binding

PMID:15448137[2]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

GO:0000978

RNA polymerase II core promoter proximal region sequence-specific DNA binding

PMID:8557039[3]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

GO:0000978

RNA polymerase II core promoter proximal region sequence-specific DNA binding

PMID:9135083[1]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

GO:0000982

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity

PMID:20032302[4]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

GO:0001077

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription

PMID:10455235[5]

IMP: Inferred from Mutant Phenotype

F

Seeded From UniProt

GO:0001077

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription

PMID:11751918[6]

IMP: Inferred from Mutant Phenotype

F

Seeded From UniProt

GO:0001077

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription

PMID:12787490[7]

IMP: Inferred from Mutant Phenotype

F

Seeded From UniProt

GO:0001077

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription

PMID:15164362[8]

IMP: Inferred from Mutant Phenotype

F

Seeded From UniProt

GO:0001077

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription

PMID:15164362[8]

IMP: Inferred from Mutant Phenotype

F

Seeded From UniProt

GO:0001077

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription

PMID:18003976[9]

IMP: Inferred from Mutant Phenotype

F

Seeded From UniProt

GO:0001077

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription

PMID:18410345[10]

IMP: Inferred from Mutant Phenotype

F

Seeded From UniProt

GO:0001077

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription

PMID:20032302[4]

IMP: Inferred from Mutant Phenotype

F

Seeded From UniProt

GO:0003677

DNA binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

Seeded From UniProt

GO:0003700

sequence-specific DNA binding transcription factor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004827

F

Seeded From UniProt

GO:0003723

RNA binding

PMID:7518718[11]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

GO:0005515

protein binding

GO_REF:0000001

IPI: Inferred from Physical Interaction

PomBase:SPAC24B11.06c

F

Seeded From UniProt

GO:0005634

nucleus

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

Seeded From UniProt

GO:0005634

nucleus

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

GO:0005634

nucleus

PMID:16823372[12]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

GO:0006351

transcription, DNA-templated

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

Seeded From UniProt

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004827

P

Seeded From UniProt

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

Seeded From UniProt

GO:0006995

cellular response to nitrogen starvation

PMID:15448137[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0007126

meiotic nuclear division

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0469

P

Seeded From UniProt

GO:0009267

cellular response to starvation

PMID:8557039[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0009267

cellular response to starvation

PMID:9135083[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0010520

regulation of reciprocal meiotic recombination

PMID:9391101[13]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0010844

recombination hotspot binding

PMID:7958849[14]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

GO:0010846

activation of reciprocal meiotic recombination

PMID:9391101[13]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0010847

regulation of chromatin assembly

PMID:15448137[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0010848

regulation of chromatin disassembly

PMID:15448137[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0031990

mRNA export from nucleus in response to heat stress

PMID:15840944[15]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0036129

negative regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide

PMID:9585505[16]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0042803

protein homodimerization activity

PMID:7958849[14]

IPI: Inferred from Physical Interaction

PomBase:SPBC29B5.01

F

Seeded From UniProt

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004827

F

Seeded From UniProt

GO:0043565

sequence-specific DNA binding

PMID:7958849[14]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

GO:0043949

regulation of cAMP-mediated signaling

PMID:15448137[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0045128

negative regulation of reciprocal meiotic recombination

PMID:18375981[17]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:0046982

protein heterodimerization activity

PMID:7958849[14]

IPI: Inferred from Physical Interaction

PomBase:SPAC21E11.03c

F

Seeded From UniProt

GO:0051039

positive regulation of transcription during meiosis

PMID:8557039[3]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

GO:0070301

cellular response to hydrogen peroxide

PMID:16087744[18]

IGI: Inferred from Genetic Interaction

PomBase:SPAC1783.07c

P

Seeded From UniProt

GO:1900411

regulation of histone acetylation by regulation of transcription from RNA polymerase II promoter

PMID:15218150[19]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

GO:1900412

regulation of histone methylation by regulation of transcription from RNA polymerase II promoter

PMID:15218150[19]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

NOT

GO:0034599

cellular response to oxidative stress

PMID:9585505[16]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

NOT

GO:0046685

response to arsenic-containing substance

PMID:16087744[18]

IGI: Inferred from Genetic Interaction

PomBase:SPAC1783.07c

P

Seeded From UniProt

NOT

GO:0071243

cellular response to arsenic-containing substance

PMID:9585505[16]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

NOT

GO:0071276

cellular response to cadmium ion

PMID:9585505[16]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt


Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Kanoh, J et al. (1996) Schizosaccharomyces pombe gad7+ encodes a phosphoprotein with a bZIP domain, which is required for proper G1 arrest and gene expression under nitrogen starvation. Genes Cells 1 391-408 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Davidson, MK et al. (2004) Atf1-Pcr1-M26 complex links stress-activated MAPK and cAMP-dependent protein kinase pathways via chromatin remodeling of cgs2+. J. Biol. Chem. 279 50857-63 PubMed GONUTS page
  3. 3.0 3.1 3.2 Takeda, T et al. (1995) Schizosaccharomyces pombe atf1+ encodes a transcription factor required for sexual development and entry into stationary phase. EMBO J. 14 6193-208 PubMed GONUTS page
  4. 4.0 4.1 Takada, H et al. (2010) The cell surface protein gene ecm33+ is a target of the two transcription factors Atf1 and Mbx1 and negatively regulates Pmk1 MAPK cell integrity signaling in fission yeast. Mol. Biol. Cell 21 674-85 PubMed GONUTS page
  5. Yamada, K et al. (1999) Schizosaccharomyces pombe homologue of glutathione peroxidase, which does not contain selenocysteine, is induced by several stresses and works as an antioxidant. Yeast 15 1125-32 PubMed GONUTS page
  6. Taricani, L et al. (2002) The fission yeast ES2 homologue, Bis1, interacts with the Ish1 stress-responsive nuclear envelope protein. J. Biol. Chem. 277 10562-72 PubMed GONUTS page
  7. Kim, SJ et al. (2003) Regulation of the gene encoding glutathione synthetase from the fission yeast. J. Biochem. Mol. Biol. 36 326-31 PubMed GONUTS page
  8. 8.0 8.1 Paredes, V et al. (2004) Transcriptional and post-translational regulation of neutral trehalase in Schizosaccharomyces pombe during thermal stress. Yeast 21 593-603 PubMed GONUTS page
  9. Chen, D et al. (2008) Multiple pathways differentially regulate global oxidative stress responses in fission yeast. Mol. Biol. Cell 19 308-17 PubMed GONUTS page
  10. Sundaram, G et al. (2008) Characterization of Sro1, a novel stress responsive protein in Schizosaccharomyces pombe. FEMS Yeast Res. 8 564-73 PubMed GONUTS page
  11. Wahls, WP (1994) RNA associated with a heterodimeric protein that activates a meiotic homologous recombination hot spot: RL/RT/PCR strategy for cloning any unknown RNA or DNA. PCR Methods Appl. 3 272-7 PubMed GONUTS page
  12. Matsuyama, A et al. (2006) ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat. Biotechnol. 24 841-7 PubMed GONUTS page
  13. 13.0 13.1 Kon, N et al. (1997) Transcription factor Mts1/Mts2 (Atf1/Pcr1, Gad7/Pcr1) activates the M26 meiotic recombination hotspot in Schizosaccharomyces pombe. Proc. Natl. Acad. Sci. U.S.A. 94 13765-70 PubMed GONUTS page
  14. 14.0 14.1 14.2 14.3 Wahls, WP & Smith, GR (1994) A heteromeric protein that binds to a meiotic homologous recombination hot spot: correlation of binding and hot spot activity. Genes Dev. 8 1693-702 PubMed GONUTS page
  15. Yoshida, J & Tani, T (2005) Hsp16p is required for thermotolerance in nuclear mRNA export in fission yeast Schizosaccharomyces pombe. Cell Struct. Funct. 29 125-38 PubMed GONUTS page
  16. 16.0 16.1 16.2 16.3 Toone, WM et al. (1998) Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1. Genes Dev. 12 1453-63 PubMed GONUTS page
  17. Gao, J et al. (2008) Distinct regions of ATF/CREB proteins Atf1 and Pcr1 control recombination hotspot ade6-M26 and the osmotic stress response. Nucleic Acids Res. 36 2838-51 PubMed GONUTS page
  18. 18.0 18.1 Rodríguez-Gabriel, MA & Russell, P (2005) Distinct signaling pathways respond to arsenite and reactive oxygen species in Schizosaccharomyces pombe. Eukaryotic Cell 4 1396-402 PubMed GONUTS page
  19. 19.0 19.1 Jia, S et al. (2004) RNAi-independent heterochromatin nucleation by the stress-activated ATF/CREB family proteins. Science 304 1971-6 PubMed GONUTS page