SALTY:SOPE

Species (Taxon ID)	Salmonella typhimurium. (90371)
Gene Name(s)	sopE
Protein Name(s)	Guanine nucleotide exchange factor sopE Effector protein sopE Toxin sopE
External Links
UniProt	O52623
EMBL	AF043239
RefSeq	YP_005182570.1
PDB	1GZS
PDBsum	1GZS
ProteinModelPortal	O52623
SMR	O52623
IntAct	O52623
EvolutionaryTrace	O52623
GO	GO:0005576 GO:0005096 GO:0005085 GO:0005515 GO:0031532 GO:0032862 GO:0009405
InterPro	IPR005414 IPR016019 IPR016018
Pfam	PF05364 PF07487
PIRSF	PIRSF034781
PRINTS	PR01593
SUPFAM	SSF81832

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0007256	activation of JNKK activity	PMID:9630225	ECO:0000314			P		Figure 2. SopE Induces JNK Activation. A vector containing JNK and a vector containing SopE were inserted into COS-1 cells and activities were measured in an immunocomplex kinase assay. The increased activity of JNK in the presence of SopE was seen using immunoblot analyses.	complete
enables	GO:0005085	guanyl-nucleotide exchange factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005414 InterPro:IPR016019	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005414	C		Seeded From UniProt	complete
involved_in	GO:0009405	pathogenesis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005414 InterPro:IPR016019	P		Seeded From UniProt	complete
involved_in	GO:0031532	actin cytoskeleton reorganization	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005414 InterPro:IPR016019	P		Seeded From UniProt	complete
involved_in	GO:0090630	activation of GTPase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005414 InterPro:IPR016019	P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
enables	GO:0005085	guanyl-nucleotide exchange factor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0344	F		Seeded From UniProt	complete
enables	GO:0005096	GTPase activator activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0343	F		Seeded From UniProt	complete
involved_in	GO:0009405	pathogenesis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0843	P		Seeded From UniProt	complete
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