GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

RICPR:TLCD

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Rickettsia prowazekii (strain Madrid E). (272947)
Gene Name(s) tlcD (synonyms: tlc4)
Protein Name(s) ADP,ATP carrier protein 4

ADP/ATP translocase 4

External Links
UniProt Q9ZD47
EMBL AJ235272
PIR F71653
RefSeq NP_220876.1
ProteinModelPortal Q9ZD47
STRING 272947.RP500
TCDB 2.A.12.1.4
EnsemblBacteria CAA14952
GeneID 883144
KEGG rpr:RP500
PATRIC 17901782
eggNOG COG3202
HOGENOM HOG000238123
KO K03301
OMA FLMTAIY
OrthoDB EOG6BCSND
Proteomes UP000002480
GO GO:0016021
GO:0005886
GO:0005524
GO:0005471
GO:0015931
InterPro IPR004667
PANTHER PTHR31187:SF0
Pfam PF03219
TIGRFAMs TIGR00769

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0006810

transport

PMID:16923893[1]

ECO:0000314

P

Figure 2A

complete
CACAO 3809

GO:0015931

nucleobase-containing compound transport

PMID:16923893[1]

ECO:0000314

P

The Tlc4 gene was cloned into the pET-11a expression vector and introduced into the C41 strain of E. coli by electroporation. Using filtration uptake assays, it was shown, as seen in figure 2A, that Tlc4 was able to transport CTP, UTP, and GDP with very similar maximum rates in the E. coli expression vector. CTP (.1 mM) bound the most avidly followed by UTP (.3 mM) and then GDP (.6 mM).

complete
CACAO 3983

involved_in

GO:0015931

nucleobase-containing compound transport

PMID:16923893[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0015866

ADP transport

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005471

P

Seeded From UniProt

complete

involved_in

GO:0015867

ATP transport

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005471

P

Seeded From UniProt

complete

enables

GO:0005471

ATP:ADP antiporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004667

F

Seeded From UniProt

complete

involved_in

GO:0006862

nucleotide transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004667

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004667

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Audia, JP & Winkler, HH (2006) Study of the five Rickettsia prowazekii proteins annotated as ATP/ADP translocases (Tlc): Only Tlc1 transports ATP/ADP, while Tlc4 and Tlc5 transport other ribonucleotides. J. Bacteriol. 188 6261-8 PubMed GONUTS page