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RAT:VAMP8
Contents
| Species (Taxon ID) | Rattus norvegicus (Rat). (10116) | |
| Gene Name(s) | Vamp8 (ECO:0000303 with PMID:10336434[1]) | |
| Protein Name(s) | Vesicle-associated membrane protein 8 (ECO:0000303 with PMID:10336434[1])
VAMP-8 (ECO:0000303 with PMID:10336434[1]) Endobrevin (ECO:0000250 with UniProtKB:Q9BV40) EDB (ECO:0000250 with UniProtKB:Q9BV40) | |
| External Links | ||
| UniProt | Q9WUF4 | |
| EMBL | AF132812 | |
| RefSeq | NP_114015.1 | |
| UniGene | Rn.82672 | |
| PDB | 1GL2 | |
| PDBsum | 1GL2 | |
| ProteinModelPortal | Q9WUF4 | |
| SMR | Q9WUF4 | |
| CORUM | Q9WUF4 | |
| DIP | DIP-43964N | |
| IntAct | Q9WUF4 | |
| MINT | MINT-4570149 | |
| STRING | 10116.ENSRNOP00000017301 | |
| iPTMnet | Q9WUF4 | |
| PhosphoSitePlus | Q9WUF4 | |
| PaxDb | Q9WUF4 | |
| PRIDE | Q9WUF4 | |
| GeneID | 83730 | |
| KEGG | rno:83730 | |
| UCSC | RGD:620421 | |
| CTD | 8673 | |
| RGD | 620421 | |
| eggNOG | KOG0860 COG5143 | |
| HOGENOM | HOG000042711 | |
| HOVERGEN | HBG006675 | |
| InParanoid | Q9WUF4 | |
| KO | K08512 | |
| PhylomeDB | Q9WUF4 | |
| EvolutionaryTrace | Q9WUF4 | |
| PRO | PR:Q9WUF4 | |
| Proteomes | UP000002494 | |
| GO | GO:0031901 GO:0016021 GO:0031902 GO:0005765 GO:0030496 GO:0005886 GO:0055037 GO:0031201 GO:0008021 GO:0005484 GO:0019905 GO:0097352 GO:0006887 GO:0061025 GO:0006461 GO:0015031 GO:0006906 GO:0016192 | |
| InterPro | IPR001388 IPR016444 | |
| Pfam | PF00957 | |
| PIRSF | PIRSF005409 | |
| PRINTS | PR00219 | |
| PROSITE | PS00417 PS50892 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0030496 |
midbody |
ECO:0000314 |
C |
Rattus norvegicus, Vesicle-associated membrane protein 8 (endobrevin); In Figure 3B, it is shown through immunostaining that endobrevin localizes to the midbody of the normal rat kidney cell. |
complete | |||||
|
involved_in |
GO:0097352 |
autophagosome maturation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0065003 |
protein-containing complex assembly |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0061025 |
membrane fusion |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0055037 |
recycling endosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031902 |
late endosome membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031201 |
SNARE complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031201 |
SNARE complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0019905 |
syntaxin binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
RGD:619747 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0016192 |
vesicle-mediated transport |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006906 |
vesicle fusion |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005765 |
lysosomal membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005484 |
SNAP receptor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005484 |
SNAP receptor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016192 |
vesicle-mediated transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005768 |
endosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006914 |
autophagy |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015031 |
protein transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005764 |
lysosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031901 |
early endosome membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005765 |
lysosomal membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031902 |
late endosome membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030496 |
midbody |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Fasshauer, D et al. (1999) Mixed and non-cognate SNARE complexes. Characterization of assembly and biophysical properties. J. Biol. Chem. 274 15440-6 PubMed GONUTS page
- ↑ Low, SH et al. (2003) Syntaxin 2 and endobrevin are required for the terminal step of cytokinesis in mammalian cells. Dev. Cell 4 753-9 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Sakiyama, H et al. (2009) Membrane fusion between liposomes containing SNARE proteins involved in mast cell exocytosis. Inflamm. Res. 58 139-42 PubMed GONUTS page
- ↑ Vergés, M et al. (1999) A tubular endosomal fraction from rat liver: biochemical evidence of receptor sorting by default. Proc. Natl. Acad. Sci. U.S.A. 96 10146-51 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 Pryor, PR et al. (2004) Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events. EMBO Rep. 5 590-5 PubMed GONUTS page
- ↑ Antonin, W et al. (2002) Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs. Nat. Struct. Biol. 9 107-11 PubMed GONUTS page
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