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RAT:THTPA
Contents
| Species (Taxon ID) | Rattus norvegicus (Rat). (10116) | |
| Gene Name(s) | Thtpa | |
| Protein Name(s) | Thiamine-triphosphatase
ThTPase | |
| External Links | ||
| UniProt | Q8CGV7 | |
| EMBL | BC081978 AY065967 | |
| RefSeq | NP_001007683.1 | |
| UniGene | Rn.163276 | |
| ProteinModelPortal | Q8CGV7 | |
| SMR | Q8CGV7 | |
| STRING | 10116.ENSRNOP00000038507 | |
| iPTMnet | Q8CGV7 | |
| PaxDb | Q8CGV7 | |
| PRIDE | Q8CGV7 | |
| Ensembl | ENSRNOT00000034073 | |
| GeneID | 305889 | |
| KEGG | rno:305889 | |
| UCSC | RGD:727917 | |
| CTD | 79178 | |
| RGD | 727917 | |
| eggNOG | ENOG410J0T6 ENOG4111XGF | |
| GeneTree | ENSGT00390000005996 | |
| HOGENOM | HOG000154571 | |
| HOVERGEN | HBG057173 | |
| InParanoid | Q8CGV7 | |
| KO | K05307 | |
| OMA | RDTYYDT | |
| OrthoDB | EOG7288SN | |
| PhylomeDB | Q8CGV7 | |
| TreeFam | TF333398 | |
| BRENDA | 3.6.1.28 | |
| Reactome | R-RNO-196819 | |
| NextBio | 655197 | |
| PRO | PR:Q8CGV7 | |
| Proteomes | UP000002494 | |
| ExpressionAtlas | Q8CGV7 | |
| Genevisible | Q8CGV7 | |
| GO | GO:0005737 GO:0000287 GO:0050333 GO:0042357 GO:0006772 | |
| Gene3D | 2.40.320.10 | |
| InterPro | IPR023577 IPR012177 | |
| Pfam | PF01928 | |
| PIRSF | PIRSF036561 | |
| SUPFAM | SSF55154 | |
| PROSITE | PS51707 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0015888 |
thiamine transport |
ECO:0000314 |
P |
Both cell membrane thiamin transporters and mitochondrial thiamin pyrophosphate transporter expression levels were suppressed after 2 days of induced Sepsis. Sepsis inhibits carrier-mediated intestinal thiamin uptake as a function of sepsis severity |
complete | |||||
|
enables |
GO:0050333 |
thiamin-triphosphatase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050333 |
thiamin-triphosphatase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042357 |
thiamine diphosphate metabolic process |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050333 |
thiamin-triphosphatase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2446078 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042357 |
thiamine diphosphate metabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2446078 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0016311 |
dephosphorylation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001026440 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2446078 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006772 |
thiamine metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050333 |
thiamin-triphosphatase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050333 |
thiamin-triphosphatase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Sassoon, CS et al. (2016) Inhibition of Intestinal Thiamin Transport in Rat Model of Sepsis. Crit. Care Med. PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
