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RAT:TGM1

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Species (Taxon ID) Rattus norvegicus (Rat). (10116)
Gene Name(s) Tgm1
Protein Name(s) Protein-glutamine gamma-glutamyltransferase K

Epidermal TGase Transglutaminase K TG(K) TGK TGase K Transglutaminase-1 TGase-1

External Links
UniProt P23606
EMBL M57263
BC097305
PIR B38423
RefSeq NP_113847.1
XP_006252076.1
XP_008768913.1
UniGene Rn.10039
ProteinModelPortal P23606
BioGrid 248784
STRING 10116.ENSRNOP00000027315
PhosphoSite P23606
PaxDb P23606
PRIDE P23606
Ensembl ENSRNOT00000027315
GeneID 60335
KEGG rno:60335
UCSC RGD:61838
CTD 7051
RGD 61838
eggNOG NOG80379
GeneTree ENSGT00760000119108
HOGENOM HOG000231695
HOVERGEN HBG004342
InParanoid P23606
KO K05619
OMA GRWGGNP
OrthoDB EOG7WT40M
PhylomeDB P23606
TreeFam TF324278
NextBio 611983
PRO PR:P23606
Proteomes UP000002494
Genevestigator P23606
GO GO:0005913
GO:0070062
GO:0031224
GO:0046872
GO:0003810
GO:0031424
GO:0009887
GO:0018149
Gene3D 2.60.40.10
3.90.260.10
InterPro IPR023608
IPR013783
IPR014756
IPR002931
IPR008958
IPR013808
IPR001102
PANTHER PTHR11590
Pfam PF00927
PF01841
PF00868
PIRSF PIRSF000459
SMART SM00460
SUPFAM SSF49309
SSF81296
PROSITE PS00547

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0045787

positive regulation of cell cycle

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P22735

P

Seeded From UniProt

complete

involved_in

GO:0010838

positive regulation of keratinocyte proliferation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P22735

P

Seeded From UniProt

complete

involved_in

GO:0018149

peptide cross-linking

PMID:1979171[1]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005575

cellular_component

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003810

protein-glutamine gamma-glutamyltransferase activity

PMID:1979171[1]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0045787

positive regulation of cell cycle

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22735
ensembl:ENSP00000206765

P

Seeded From UniProt

complete

part_of

GO:0031224

intrinsic component of membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22735
ensembl:ENSP00000206765

C

Seeded From UniProt

complete

involved_in

GO:0030216

keratinocyte differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22735
ensembl:ENSP00000206765

P

Seeded From UniProt

complete

involved_in

GO:0018149

peptide cross-linking

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22735
ensembl:ENSP00000206765

P

Seeded From UniProt

complete

involved_in

GO:0010838

positive regulation of keratinocyte proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22735
ensembl:ENSP00000206765

P

Seeded From UniProt

complete

enables

GO:0003810

protein-glutamine gamma-glutamyltransferase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22735
ensembl:ENSP00000206765

F

Seeded From UniProt

complete

enables

GO:0003810

protein-glutamine gamma-glutamyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008958
InterPro:IPR023608
InterPro:IPR036238

F

Seeded From UniProt

complete

involved_in

GO:0018149

peptide cross-linking

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001102
InterPro:IPR008958
InterPro:IPR013808
InterPro:IPR023608
InterPro:IPR036238

P

Seeded From UniProt

complete

enables

GO:0003810

protein-glutamine gamma-glutamyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.3.2.13

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

enables

GO:0016746

transferase activity, transferring acyl groups

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0012

F

Seeded From UniProt

complete

involved_in

GO:0031424

keratinization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0417

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Phillips, MA et al. (1990) Primary structure of keratinocyte transglutaminase. Proc. Natl. Acad. Sci. U.S.A. 87 9333-7 PubMed GONUTS page