RAT:SC6A4

Species (Taxon ID)	Rattus norvegicus (Rat). (10116)
Gene Name(s)	Slc6a4
Protein Name(s)	Sodium-dependent serotonin transporter 5HT transporter 5HTT Solute carrier family 6 member 4
External Links
UniProt	P31652
EMBL	X63995 X63253 M79450 Y11024
PIR	S19585 S30604
RefSeq	NP_037166.2 XP_008766172.1
UniGene	Rn.1663
ProteinModelPortal	P31652
IntAct	P31652
BindingDB	P31652
ChEMBL	CHEMBL2096672
GuidetoPHARMACOLOGY	928
Ensembl	ENSRNOT00000004717
GeneID	25553
KEGG	rno:25553
CTD	6532
RGD	3714
eggNOG	COG0733
GeneTree	ENSGT00760000118857
HOGENOM	HOG000116406
HOVERGEN	HBG071421
InParanoid	P31652
KO	K05037
OMA	TSCKNSW
OrthoDB	EOG793B71
PhylomeDB	P31652
TreeFam	TF343812
NextBio	607109
PRO	PR:P31652
Proteomes	UP000002494
Genevestigator	P31652
GO	GO:0005829 GO:0012505 GO:0010008 GO:0005887 GO:0045121 GO:0043005 GO:0005886 GO:0051015 GO:0019811 GO:0017022 GO:0042803 GO:0015222 GO:0005335 GO:0017075 GO:0007420 GO:0048854 GO:0071321 GO:0071300 GO:0007623 GO:0007626 GO:0007613 GO:0021941 GO:0045665 GO:0046621 GO:0032227 GO:0045787 GO:0010628 GO:0051260 GO:0051259 GO:0042493 GO:0032355 GO:0001666 GO:0007584 GO:0010033 GO:0009636 GO:0006837 GO:0051610 GO:0035176 GO:0042713 GO:0021794 GO:0042310
InterPro	IPR000175 IPR013086
PANTHER	PTHR11616
Pfam	PF03491 PF00209
PRINTS	PR01203 PR00176
PROSITE	PS00610 PS00754 PS50267

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0090067	regulation of thalamus size	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P31645	P		Seeded From UniProt	complete
involved_in	GO:0051610	serotonin uptake	PMID:15627510^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0051610	serotonin uptake	PMID:14642278^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0051260	protein homooligomerization	PMID:12944413^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0051259	protein complex oligomerization	PMID:10716733^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0051015	actin filament binding	PMID:15627510^[1]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0017075	syntaxin-1 binding	PMID:11709063^[5]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P32851	F		Seeded From UniProt	complete
enables	GO:0017075	syntaxin-1 binding	PMID:14642278^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P32851	F		Seeded From UniProt	complete
enables	GO:0017022	myosin binding	PMID:12944413^[3]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q62812	F		Seeded From UniProt	complete
enables	GO:0005335	serotonin:sodium symporter activity	PMID:11709063^[5]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0012505	endomembrane system	PMID:16870614^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0012505	endomembrane system	PMID:10716733^[4]	ECO:0000303	author statement without traceable support used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0006837	serotonin transport	PMID:11709063^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:15627510^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:11709063^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:10716733^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005335	serotonin:sodium symporter activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P31645	F		Seeded From UniProt	complete
part_of	GO:0099154	serotonergic synapse	PMID:10460242^[7]	ECO:0006003	electron microscopy evidence used in manual assertion		C	part_of:(UBERON:0002435)	Seeded From UniProt	complete
part_of	GO:0099056	integral component of presynaptic membrane	PMID:10460242^[7]	ECO:0006003	electron microscopy evidence used in manual assertion		C	part_of:(GO:0099154) part_of:(UBERON:0002435)	Seeded From UniProt	complete
part_of	GO:0099055	integral component of postsynaptic membrane	PMID:10460242^[7]	ECO:0006003	electron microscopy evidence used in manual assertion		C	part_of:(UBERON:0002435)	Seeded From UniProt	complete
involved_in	GO:0071321	cellular response to cGMP	PMID:17310063^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0071300	cellular response to retinoic acid	PMID:17895527^[9]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0051610	serotonin uptake	PMID:12944413^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045665	negative regulation of neuron differentiation	PMID:18573488^[10]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	PMID:15226315^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	PMID:17310063^[8]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	PMID:12944413^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0042713	sperm ejaculation	PMID:20704641^[12]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042493	response to drug	PMID:20501324^[13]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042310	vasoconstriction	PMID:14605793^[14]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032355	response to estradiol	PMID:19168037^[15]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032227	negative regulation of synaptic transmission, dopaminergic	PMID:20730799^[16]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0021941	negative regulation of cerebellar granule cell precursor proliferation	PMID:18573488^[10]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0019811	cocaine binding	PMID:15994310^[17]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0014064	positive regulation of serotonin secretion	PMID:25261262^[18]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010033	response to organic substance	PMID:20002520^[19]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007626	locomotory behavior	PMID:12220705^[20]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007623	circadian rhythm	PMID:18482738^[21]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007613	memory	PMID:20730799^[16]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007584	response to nutrient	PMID:21068163^[22]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007420	brain development	PMID:20127812^[23]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006837	serotonin transport	PMID:15994310^[17]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0005335	serotonin:sodium symporter activity	PMID:15994310^[17]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0001666	response to hypoxia	PMID:11259539^[24]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0051610	serotonin uptake	PMID:21873635^[25]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010414 MGI:MGI:96285 PANTHER:PTN002481010 RGD:3714 UniProtKB:P31645 WB:WBGene00003387	P		Seeded From UniProt	complete
enables	GO:0051378	serotonin binding	PMID:21873635^[25]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002481010 UniProtKB:F1MLI6 UniProtKB:Q9XT49	F		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	PMID:21873635^[25]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002481010 RGD:3714	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[25]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0035969 FB:FBgn0039915 MGI:MGI:1336891 MGI:MGI:1336892 MGI:MGI:95627 MGI:MGI:95760 PANTHER:PTN000177662 RGD:3714 RGD:3715 RGD:620533 RGD:621822 UniProtKB:P31645 UniProtKB:Q01959 UniProtKB:Q9Y345	C		Seeded From UniProt	complete
enables	GO:0005335	serotonin:sodium symporter activity	PMID:21873635^[25]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010414 PANTHER:PTN002481010 RGD:3714 UniProtKB:P31645 WB:WBGene00003387	F		Seeded From UniProt	complete
involved_in	GO:0055085	transmembrane transport	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0015293	P		Seeded From UniProt	complete
involved_in	GO:0090067	regulation of thalamus size	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31645 ensembl:ENSP00000261707	P		Seeded From UniProt	complete
involved_in	GO:0051610	serotonin uptake	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31645 ensembl:ENSP00000261707	P		Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31645 ensembl:ENSP00000261707	C		Seeded From UniProt	complete
enables	GO:0017137	Rab GTPase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31645 ensembl:ENSP00000261707	F		Seeded From UniProt	complete
involved_in	GO:0015844	monoamine transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31645 ensembl:ENSP00000261707	P		Seeded From UniProt	complete
part_of	GO:0012505	endomembrane system	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31645 ensembl:ENSP00000261707	C		Seeded From UniProt	complete
involved_in	GO:0009636	response to toxic substance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31645 ensembl:ENSP00000261707	P		Seeded From UniProt	complete
enables	GO:0008504	monoamine transmembrane transporter activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31645 ensembl:ENSP00000261707	F		Seeded From UniProt	complete
involved_in	GO:0006837	serotonin transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31645 ensembl:ENSP00000261707	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31645 ensembl:ENSP00000261707	C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31645 ensembl:ENSP00000261707	C		Seeded From UniProt	complete
enables	GO:0005335	serotonin:sodium symporter activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P31645 ensembl:ENSP00000261707	F		Seeded From UniProt	complete
involved_in	GO:0071310	cellular response to organic substance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60857 ensembl:ENSMUSP00000104039	P		Seeded From UniProt	complete
involved_in	GO:0051610	serotonin uptake	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60857 ensembl:ENSMUSP00000104039	P		Seeded From UniProt	complete
enables	GO:0050998	nitric-oxide synthase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60857 ensembl:ENSMUSP00000104039	F		Seeded From UniProt	complete
involved_in	GO:0048854	brain morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60857 ensembl:ENSMUSP00000104039	P		Seeded From UniProt	complete
involved_in	GO:0046621	negative regulation of organ growth	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60857 ensembl:ENSMUSP00000104039	P		Seeded From UniProt	complete
involved_in	GO:0045787	positive regulation of cell cycle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60857 ensembl:ENSMUSP00000104039	P		Seeded From UniProt	complete
involved_in	GO:0035176	social behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60857 ensembl:ENSMUSP00000104039	P		Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60857 ensembl:ENSMUSP00000104039	P		Seeded From UniProt	complete
involved_in	GO:0006837	serotonin transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q60857 ensembl:ENSMUSP00000104039	P		Seeded From UniProt	complete
enables	GO:0005328	neurotransmitter:sodium symporter activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR037272	F		Seeded From UniProt	complete
enables	GO:0005335	serotonin:sodium symporter activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR013086	F		Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR013086	C		Seeded From UniProt	complete
involved_in	GO:0006836	neurotransmitter transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR013086	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000175	C		Seeded From UniProt	complete
involved_in	GO:0006837	serotonin transport	PMID:12220705^[20]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0005335	serotonin:sodium symporter activity	PMID:12220705^[20]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0006836	neurotransmitter transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0532	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
enables	GO:0015293	symporter activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0769	F		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0967	C		Seeded From UniProt	complete
part_of	GO:0012505	endomembrane system	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0147	C		Seeded From UniProt	complete
part_of	GO:0010008	endosome membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0100	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 Mochizuki, H et al. (2005) Role of C-terminal region in the functional regulation of rat serotonin transporter (SERT). Neurochem. Int. 46 93-105 PubMed GONUTS page
↑ ^2.0 ^2.1 Quick, MW (2003) Regulating the conducting states of a mammalian serotonin transporter. Neuron 40 537-49 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 Ozaslan, D et al. (2003) Glycosyl modification facilitates homo- and hetero-oligomerization of the serotonin transporter. A specific role for sialic acid residues. J. Biol. Chem. 278 43991-4000 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 Kilic, F & Rudnick, G (2000) Oligomerization of serotonin transporter and its functional consequences. Proc. Natl. Acad. Sci. U.S.A. 97 3106-11 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 Haase, J et al. (2001) Regulation of the serotonin transporter by interacting proteins. Biochem. Soc. Trans. 29 722-8 PubMed GONUTS page
↑ Müller, HK et al. (2006) Subcellular redistribution of the serotonin transporter by secretory carrier membrane protein 2. J. Biol. Chem. 281 28901-9 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 Pickel, VM & Chan, J (1999) Ultrastructural localization of the serotonin transporter in limbic and motor compartments of the nucleus accumbens. J. Neurosci. 19 7356-66 PubMed GONUTS page
↑ ^8.0 ^8.1 Ramamoorthy, S et al. (2007) Phosphorylation of threonine residue 276 is required for acute regulation of serotonin transporter by cyclic GMP. J. Biol. Chem. 282 11639-47 PubMed GONUTS page
↑ O'Reilly, KC et al. (2007) 13-cis-Retinoic acid alters intracellular serotonin, increases 5-HT1A receptor, and serotonin reuptake transporter levels in vitro. Exp. Biol. Med. (Maywood) 232 1195-203 PubMed GONUTS page
↑ ^10.0 ^10.1 Zusso, M et al. (2008) Fluoxetine-induced proliferation and differentiation of neural progenitor cells isolated from rat postnatal cerebellum. Biochem. Pharmacol. 76 391-403 PubMed GONUTS page
↑ Magnani, F et al. (2004) Partitioning of the serotonin transporter into lipid microdomains modulates transport of serotonin. J. Biol. Chem. 279 38770-8 PubMed GONUTS page
↑ Chan, JS et al. (2011) The serotonin transporter plays an important role in male sexual behavior: a study in serotonin transporter knockout rats. J Sex Med 8 97-108 PubMed GONUTS page
↑ Sato, H et al. (2010) Chronic buspirone treatment decreases 5-HT1B receptor densities and the serotonin transporter but increases the density of 5-HT2A receptors in the bulbectomized rat model of depression: an autoradiographic study. Brain Res. 1345 28-44 PubMed GONUTS page
↑ Wanstall, JC et al. (2003) Potentiation of 5-hydroxytryptamine (5-HT) responses by a 5-HT uptake inhibitor in pulmonary and systemic vessels: effects of exposing rats to hypoxia. Naunyn Schmiedebergs Arch. Pharmacol. 368 520-7 PubMed GONUTS page
↑ Rivera, HM et al. (2009) Estradiol increases Pet-1 and serotonin transporter mRNA in the midbrain raphe nuclei of ovariectomized rats. Brain Res. 1259 51-8 PubMed GONUTS page
↑ ^16.0 ^16.1 Schilström, B et al. (2011) Effects of S-citalopram, citalopram, and R-citalopram on the firing patterns of dopamine neurons in the ventral tegmental area, N-methyl-D-aspartate receptor-mediated transmission in the medial prefrontal cortex and cognitive function in the rat. Synapse 65 357-67 PubMed GONUTS page
↑ ^17.0 ^17.1 ^17.2 Zhang, YW & Rudnick, G (2005) Cysteine-scanning mutagenesis of serotonin transporter intracellular loop 2 suggests an alpha-helical conformation. J. Biol. Chem. 280 30807-13 PubMed GONUTS page
↑ Verheij, MM et al. (2014) Reduced cocaine-induced serotonin, but not dopamine and noradrenaline, release in rats with a genetic deletion of serotonin transporters. Eur Neuropsychopharmacol 24 1850-4 PubMed GONUTS page
↑ Biezonski, DK & Meyer, JS (2010) Effects of 3,4-methylenedioxymethamphetamine (MDMA) on serotonin transporter and vesicular monoamine transporter 2 protein and gene expression in rats: implications for MDMA neurotoxicity. J. Neurochem. 112 951-62 PubMed GONUTS page
↑ ^20.0 ^20.1 ^20.2 Zhang, K et al. (2002) Serotonin transporter binding increases in caudate-putamen and nucleus accumbens after neonatal 6-hydroxydopamine lesions in rats: implications for motor hyperactivity. Brain Res. Dev. Brain Res. 137 135-8 PubMed GONUTS page
↑ Nomura, K et al. (2008) Selective serotonin reuptake inhibitors and raft inhibitors shorten the period of Period1-driven circadian bioluminescence rhythms in rat-1 fibroblasts. Life Sci. 82 1169-74 PubMed GONUTS page
↑ Bertrand, RL et al. (2011) A Western diet increases serotonin availability in rat small intestine. Endocrinology 152 36-47 PubMed GONUTS page
↑ Liu, Q & Wong-Riley, MT (2010) Postnatal changes in tryptophan hydroxylase and serotonin transporter immunoreactivity in multiple brainstem nuclei of the rat: implications for a sensitive period. J. Comp. Neurol. 518 1082-97 PubMed GONUTS page
↑ Eddahibi, S et al. (2001) Dexfenfluramine-associated changes in 5-hydroxytryptamine transporter expression and development of hypoxic pulmonary hypertension in rats. J. Pharmacol. Exp. Ther. 297 148-54 PubMed GONUTS page
↑ ^25.0 ^25.1 ^25.2 ^25.3 ^25.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:15627510-1] 1.0 ^1.1 ^1.2 Mochizuki, H et al. (2005) Role of C-terminal region in the functional regulation of rat serotonin transporter (SERT). Neurochem. Int. 46 93-105 PubMed GONUTS page

[PMID:14642278-2] 2.0 ^2.1 Quick, MW (2003) Regulating the conducting states of a mammalian serotonin transporter. Neuron 40 537-49 PubMed GONUTS page

[PMID:12944413-3] 3.0 ^3.1 ^3.2 ^3.3 Ozaslan, D et al. (2003) Glycosyl modification facilitates homo- and hetero-oligomerization of the serotonin transporter. A specific role for sialic acid residues. J. Biol. Chem. 278 43991-4000 PubMed GONUTS page

[PMID:10716733-4] 4.0 ^4.1 ^4.2 Kilic, F & Rudnick, G (2000) Oligomerization of serotonin transporter and its functional consequences. Proc. Natl. Acad. Sci. U.S.A. 97 3106-11 PubMed GONUTS page

[PMID:11709063-5] 5.0 ^5.1 ^5.2 ^5.3 Haase, J et al. (2001) Regulation of the serotonin transporter by interacting proteins. Biochem. Soc. Trans. 29 722-8 PubMed GONUTS page

[PMID:16870614-6] Müller, HK et al. (2006) Subcellular redistribution of the serotonin transporter by secretory carrier membrane protein 2. J. Biol. Chem. 281 28901-9 PubMed GONUTS page

[PMID:10460242-7] 7.0 ^7.1 ^7.2 Pickel, VM & Chan, J (1999) Ultrastructural localization of the serotonin transporter in limbic and motor compartments of the nucleus accumbens. J. Neurosci. 19 7356-66 PubMed GONUTS page

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