RAT:NRAM1

Species (Taxon ID)	Rattus norvegicus (Rat). (10116)
Gene Name(s)	Slc11a1 (synonyms: Bcg, Nramp1)
Protein Name(s)	Natural resistance-associated macrophage protein 1 NRAMP 1 Solute carrier family 11 member 1
External Links
UniProt	P70553
EMBL	BC100653 U53822
RefSeq	NP_001026828.1
UniGene	Rn.105919
STRING	10116.ENSRNOP00000020491
PRIDE	P70553
GeneID	316519
KEGG	rno:316519
UCSC	RGD:1601463
CTD	6556
RGD	1601463
eggNOG	COG1914
HOGENOM	HOG000152203
HOVERGEN	HBG052665
InParanoid	P70553
KO	K12347
NextBio	670947
PRO	PR:P70553
Proteomes	UP000002494
Genevestigator	P70553
GO	GO:0016021 GO:0005215 GO:0006811 GO:0055072
HAMAP	MF_00221
InterPro	IPR001046
PANTHER	PTHR11706
Pfam	PF01566
PRINTS	PR00447
TIGRFAMs	TIGR01197

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0008150	biological_process	GO_REF:0000015	ECO:0000307	no biological data found used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005575	cellular_component	GO_REF:0000015	ECO:0000307	no biological data found used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0003674	molecular_function	GO_REF:0000015	ECO:0000307	no biological data found used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0051139	metal ion:proton antiporter activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000194440 UniProtKB:P49279 UniProtKB:P51027	F		Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000194440 UniProtKB:P49279	F		Seeded From UniProt	complete
involved_in	GO:0032496	response to lipopolysaccharide		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1345275 PANTHER:PTN000194440 UniProtKB:O77741	P		Seeded From UniProt	complete
part_of	GO:0030670	phagocytic vesicle membrane		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1345275 PANTHER:PTN000194440 UniProtKB:P49279	C		Seeded From UniProt	complete
enables	GO:0015086	cadmium ion transmembrane transporter activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG14157 PANTHER:PTN000194431 RGD:3684 TAIR:locus:2025677 TAIR:locus:2200437 UniProtKB:P49281 UniProtKB:P51027	F		Seeded From UniProt	complete
involved_in	GO:0009617	response to bacterium		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1345275 PANTHER:PTN000194440 UniProtKB:O77741 UniProtKB:P49279	P		Seeded From UniProt	complete
involved_in	GO:0006879	cellular iron ion homeostasis		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1345275 PANTHER:PTN000194440 UniProtKB:P49279	P		Seeded From UniProt	complete
involved_in	GO:0006876	cellular cadmium ion homeostasis		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000194440 UniProtKB:P49279 UniProtKB:P51027	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1345279 PANTHER:PTN000194437 UniProtKB:P49279 UniProtKB:P49281 UniProtKB:P51027	C		Seeded From UniProt	complete
enables	GO:0005384	manganese ion transmembrane transporter activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG14157 FB:FBgn0011672 MGI:MGI:1345275 PANTHER:PTN000194431 RGD:3684 TAIR:locus:2025677 TAIR:locus:2036751 UniProtKB:P49281 UniProtKB:Q6ZG85	F		Seeded From UniProt	complete
enables	GO:0005384	manganese ion transmembrane transporter activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG14157 FB:FBgn0011672 MGI:MGI:1345275 PANTHER:PTN000194431 RGD:3684 TAIR:locus:2025677 TAIR:locus:2036751 UniProtKB:P49281	F		Seeded From UniProt	complete
involved_in	GO:0070574	cadmium ion transmembrane transport	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0015086	P		Seeded From UniProt	complete
involved_in	GO:0071421	manganese ion transmembrane transport	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0005384	P		Seeded From UniProt	complete
involved_in	GO:0071421	manganese ion transmembrane transport	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0005384	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001046	C		Seeded From UniProt	complete
involved_in	GO:0030001	metal ion transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001046	P		Seeded From UniProt	complete
enables	GO:0046873	metal ion transmembrane transporter activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001046	F		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
involved_in	GO:0006811	ion transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0406	P		Seeded From UniProt	complete
involved_in	GO:0055072	iron ion homeostasis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0410	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472 UniProtKB-SubCell:SL-0162	C		Seeded From UniProt	complete
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References

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