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RAT:D3Z8N9

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Species (Taxon ID) Rattus norvegicus (Rat). (10116)
Gene Name(s) No Information Provided.
Protein Name(s) Protein Asxl2 (ECO:0000313 with Ensembl:ENSRNOP00000015827)
External Links
UniProt D3Z8N9
EMBL AABR07063303
AABR07063304
RefSeq XP_006225774.1
XP_006225775.1
XP_008774417.1
UniGene Rn.161441
Rn.226534
STRING 10116.ENSRNOP00000015827
PaxDb D3Z8N9
Ensembl ENSRNOT00000015827
GeneID 313922
CTD 55252
RGD 1304710
eggNOG ENOG410IIF3
ENOG4111F3G
GeneTree ENSGT00520000055578
InParanoid D3Z8N9
OrthoDB EOG7SXW2P
TreeFam TF328464
NextBio 35565590
Proteomes UP000002494
GO GO:0000790
GO:0005654
GO:0003677
GO:0007512
GO:0048704
GO:0003007
GO:0000122
GO:1900159
GO:0045600
GO:1902466
GO:0045672
GO:0035360
GO:0045944
InterPro IPR026905
IPR024811
IPR028020
IPR024817
PANTHER PTHR13578
PTHR13578:SF11
Pfam PF13919
PF13922

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0010884

positive regulation of lipid storage

PMID:24321552[1]

ECO:0000315

P

Figure 4B shows that ASXL2 knockdown significantly blocked intracellular lipid accumulation after the addition of 0.1 mM palmitate.

complete
CACAO 11503

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2684063
PANTHER:PTN000339786
UniProtKB:Q76L83

P

Seeded From UniProt

complete

enables

GO:0042975

peroxisome proliferator activated receptor binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2684063
PANTHER:PTN000339788
UniProtKB:Q76L83

F

Seeded From UniProt

complete

part_of

GO:0035517

PR-DUB complex

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0261823
PANTHER:PTN000339786
UniProtKB:Q8IXJ9

C

Seeded From UniProt

complete

involved_in

GO:0009887

animal organ morphogenesis

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2684063
PANTHER:PTN000339786

P

Seeded From UniProt

complete

colocalizes_with

GO:0005634

nucleus

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0261823
MGI:MGI:1922552
MGI:MGI:2684063
PANTHER:PTN000339786

C

Seeded From UniProt

complete

enables

GO:0003682

chromatin binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0261823
PANTHER:PTN000339786

F

Seeded From UniProt

complete

colocalizes_with

GO:0000790

nuclear chromatin

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1922552
PANTHER:PTN000339786

C

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q76L83
ensembl:ENSP00000383920

P

Seeded From UniProt

complete

involved_in

GO:0045600

positive regulation of fat cell differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q76L83
ensembl:ENSP00000383920

P

Seeded From UniProt

complete

enables

GO:0042975

peroxisome proliferator activated receptor binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q76L83
ensembl:ENSP00000383920

F

Seeded From UniProt

complete

involved_in

GO:0035360

positive regulation of peroxisome proliferator activated receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q76L83
ensembl:ENSP00000383920

P

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q76L83
ensembl:ENSP00000383920

C

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR026905

F

Seeded From UniProt

complete

GO:0010884

positive regulation of lipid storage

PMID:24321552[1]

ECO:0000315

P

Figure 4B shows that ASXL2 knockdown significantly blocked intracellular lipid accumulation after the addition of 0.1 mM palmitate.

complete
CACAO 11341

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Park, UH et al. (2014) Reciprocal regulation of LXRα activity by ASXL1 and ASXL2 in lipogenesis. Biochem. Biophys. Res. Commun. 443 489-94 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page