RAT:ADHX

Species (Taxon ID)	Rattus norvegicus (Rat). (10116)
Gene Name(s)	Adh5 (synonyms: Adh-2, Adh2)
Protein Name(s)	Alcohol dehydrogenase class-3 Alcohol dehydrogenase 2 Alcohol dehydrogenase 5 Alcohol dehydrogenase B2 ADH-B2 Alcohol dehydrogenase class-III Glutathione-dependent formaldehyde dehydrogenase FALDH FDH GSH-FDH S-(hydroxymethyl)glutathione dehydrogenase
External Links
UniProt	P12711
EMBL	BC083724
PIR	S00331
RefSeq	NP_001119592.1
UniGene	Rn.222115
ProteinModelPortal	P12711
SMR	P12711
STRING	10116.ENSRNOP00000031961
PRIDE	P12711
Ensembl	ENSRNOT00000017252
GeneID	100145871
KEGG	rno:100145871
CTD	128
RGD	2292706
GeneTree	ENSGT00430000030800
HOGENOM	HOG000294674
HOVERGEN	HBG000195
InParanoid	P12711
KO	K00121
OMA	RCVVDMS
OrthoDB	EOG72NRQ6
SABIO-RK	P12711
NextBio	20791466
Proteomes	UP000002494
Genevestigator	P12711
GO	GO:0005737 GO:0070062 GO:0005739 GO:0005634 GO:0004022 GO:0005504 GO:0018467 GO:0051903 GO:0008270 GO:0007568 GO:0006068 GO:0006069 GO:0046294 GO:0018119 GO:0045777 GO:0003016 GO:0032496 GO:0051409 GO:0051775 GO:0001523
Gene3D	3.40.50.720 3.90.180.10
InterPro	IPR014183 IPR013149 IPR013154 IPR002085 IPR002328 IPR011032 IPR016040
PANTHER	PTHR11695
Pfam	PF08240 PF00107
SUPFAM	SSF50129
TIGRFAMs	TIGR02818
PROSITE	PS00059

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0007568	aging	PMID:18207224	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006068	ethanol catabolic process	PMID:18207224	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm		ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus		ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0004022	alcohol dehydrogenase (NAD) activity	PMID:18207224	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG50010 FB:FBgn0011768 MGI:MGI:87929 PANTHER:PTN000191653 SGD:S000002327	F		Seeded From UniProt	complete
involved_in	GO:0046294	formaldehyde catabolic process		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG50010 MGI:MGI:87929 PANTHER:PTN000191653 SGD:S000002327	P		Seeded From UniProt	complete
enables	GO:0008270	zinc ion binding		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG50010 PANTHER:PTN000191653 RGD:621638 UniProtKB:P00325 UniProtKB:P08319 UniProtKB:P11766	F		Seeded From UniProt	complete
part_of	GO:0005829	cytosol		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG50010 PANTHER:PTN000191653 RGD:2044 TAIR:locus:2009512 TAIR:locus:2025237 UniProtKB:P00325 UniProtKB:P00326 UniProtKB:P07327 UniProtKB:P08319 UniProtKB:P40394	C		Seeded From UniProt	complete
enables	GO:0004024	alcohol dehydrogenase activity, zinc-dependent		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG50010 MGI:MGI:1349472 PANTHER:PTN000191653 UniProtKB:P00325 UniProtKB:P00326 UniProtKB:P07327 UniProtKB:P08319 UniProtKB:P28332 UniProtKB:P40394	F		Seeded From UniProt	complete
involved_in	GO:0006069	ethanol oxidation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR014183	P		Seeded From UniProt	complete
enables	GO:0008270	zinc ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002328 InterPro:IPR014183	F		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002328	F		Seeded From UniProt	complete
enables	GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR014183	F		Seeded From UniProt	complete
Contributes to	GO:0004022	alcohol dehydrogenase (NAD) activity	PMID:25641189	ECO:0000314			F		Catalyzes conversion of an alcohol + NAD+ to an aldehyde or ketone + NADH	complete CACAO 10561
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002328 InterPro:IPR013149 InterPro:IPR013154 InterPro:IPR014183	P		Seeded From UniProt	complete
enables	GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.1.1.284	F		Seeded From UniProt	complete
enables	GO:0004022	alcohol dehydrogenase (NAD) activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.1.1.1	F		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
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