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RABIT:PFKAM

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Species (Taxon ID) Oryctolagus cuniculus (Rabbit). (9986)
Gene Name(s) PFKM
Protein Name(s) ATP-dependent 6-phosphofructokinase, muscle type (ECO:0000255 with HAMAP-Rule:MF_03184)

ATP-PFK (ECO:0000255 with HAMAP-Rule:MF_03184) PFK-M 6-phosphofructokinase type A Phosphofructo-1-kinase isozyme A PFK-A Phosphohexokinase (ECO:0000255 with HAMAP-Rule:MF_03184)

External Links
UniProt P00511
EMBL M14477
M14456
M14457
M14458
M14459
M14460
M14461
M14462
M14463
M14464
M14465
M14466
M14467
M14468
M14469
M14470
M14471
M14472
M14473
M14474
M14475
M14476
PIR A26550
PDB 3O8L
3O8N
PDBsum 3O8L
3O8N
ProteinModelPortal P00511
STRING 9986.ENSOCUP00000014991
ChEMBL CHEMBL1075312
iPTMnet P00511
PRIDE P00511
eggNOG KOG2440
COG0205
HOGENOM HOG000200154
HOVERGEN HBG000976
InParanoid P00511
BRENDA 2.7.1.11
SABIO-RK P00511
UniPathway UPA00109
EvolutionaryTrace P00511
Proteomes UP000001811
GO GO:0005737
GO:0003872
GO:0005524
GO:0046872
GO:0008022
GO:0006002
GO:0061615
HAMAP MF_03184
InterPro IPR009161
IPR022953
IPR015912
IPR000023
Pfam PF00365
PIRSF PIRSF000533
PRINTS PR00476
SUPFAM SSF53784
TIGRFAMs TIGR02478
PROSITE PS00433

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0003872

6-phosphofructokinase activity

PMID:3038892[1]

ECO:0000314

F

See Figure 1.

complete
CACAO 6236

enables

GO:0003872

6-phosphofructokinase activity

PMID:3038892[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008022

protein C-terminus binding

PMID:12649290[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q93050

F

Seeded From UniProt

complete

enables

GO:0008022

protein C-terminus binding

PMID:12649290[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q9HBG4

F

Seeded From UniProt

complete

enables

GO:0008022

protein C-terminus binding

PMID:18632794[3]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q9HBG4

F

Seeded From UniProt

complete

enables

GO:0003872

6-phosphofructokinase activity

PMID:18632794[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0061615

glycolytic process through fructose-6-phosphate

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003872

P

Seeded From UniProt

complete

involved_in

GO:0061615

glycolytic process through fructose-6-phosphate

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003872

P

Seeded From UniProt

complete

involved_in

GO:0061615

glycolytic process through fructose-6-phosphate

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0003872

P

Seeded From UniProt

complete

involved_in

GO:0061615

glycolytic process through fructose-6-phosphate

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0003872

P

Seeded From UniProt

complete

involved_in

GO:0061615

glycolytic process through fructose-6-phosphate

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003872

P

Seeded From UniProt

complete

enables

GO:0003872

6-phosphofructokinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000023
InterPro:IPR009161
InterPro:IPR015912
InterPro:IPR022953
InterPro:IPR035966

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009161

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009161

C

Seeded From UniProt

complete

involved_in

GO:0006002

fructose 6-phosphate metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR022953

P

Seeded From UniProt

complete

involved_in

GO:0006096

glycolytic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000023
InterPro:IPR009161
InterPro:IPR015912
InterPro:IPR022953
InterPro:IPR035966

P

Seeded From UniProt

complete

enables

GO:0003872

6-phosphofructokinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.1.11

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000166259

C

Seeded From UniProt

complete

enables

GO:0003872

6-phosphofructokinase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000166259

F

Seeded From UniProt

complete

involved_in

GO:0006096

glycolytic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000166259

P

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0021

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0008152

metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0021

P

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

involved_in

GO:0006096

glycolytic process

GO_REF:0000037
GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0324
UniPathway:UPA00109

P

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Latshaw, SP et al. (1987) Identification of highly reactive cysteinyl and methionyl residues of rabbit muscle phosphofructokinase. J. Biol. Chem. 262 10672-7 PubMed GONUTS page
  2. 2.0 2.1 Su, Y et al. (2003) The a-subunit of the V-type H+-ATPase interacts with phosphofructokinase-1 in humans. J. Biol. Chem. 278 20013-8 PubMed GONUTS page
  3. 3.0 3.1 Su, Y et al. (2008) Human H+ATPase a4 subunit mutations causing renal tubular acidosis reveal a role for interaction with phosphofructokinase-1. Am. J. Physiol. Renal Physiol. 295 F950-8 PubMed GONUTS page