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PSEAE:Q9I4X0

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Species (Taxon ID) Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228). (208964)
Gene Name(s) mvfR (ECO:0000313 with EMBL:AAG04392.1)
Protein Name(s) Transcriptional regulator MvfR (ECO:0000313 with EMBL:AAG04392.1)
External Links
UniProt Q9I4X0
EMBL AE004091
PIR D83519
RefSeq NP_249694.1
ProteinModelPortal Q9I4X0
SMR Q9I4X0
STRING 208964.PA1003
DNASU 879994
EnsemblBacteria AAG04392
GeneID 879994
KEGG pae:PA1003
PATRIC 19836296
PseudoCAP PA1003
HOGENOM HOG000247671
OMA NIMSEAV
OrthoDB EOG6P3340
PhylomeDB Q9I4X0
Proteomes UP000002438
GO GO:0003700
GO:0044212
GO:0051349
GO:0043902
GO:0034762
GO:0006351
Gene3D 1.10.10.10
InterPro IPR005119
IPR000847
IPR011991
Pfam PF00126
PF03466
PROSITE PS50931

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

NOT

GO:0030528

transcription regulator activity

PMID:24157832[1]

ECO:0000314

F

AmpR positively regulates critical QS regulators of the Las system, Rhl system and PQS. Expression of the genes was determined by qPCR.

complete
CACAO 8939

involved_in

GO:0006355

regulation of transcription, DNA-templated

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001577438
UniProtKB:P9WMF5

P

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10490
EcoGene:EG11449
EcoGene:EG13267
PANTHER:PTN001577438

F

Seeded From UniProt

complete

involved_in

GO:0051349

positive regulation of lyase activity

PMID:14739337[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0044212

transcription regulatory region DNA binding

PMID:16735731[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0043902

positive regulation of multi-organism process

PMID:15686549[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0034762

regulation of transmembrane transport

PMID:19497948[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000847

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000847

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Balasubramanian, D et al. (2014) Deep sequencing analyses expands the Pseudomonas aeruginosa AmpR regulon to include small RNA-mediated regulation of iron acquisition, heat shock and oxidative stress response. Nucleic Acids Res. 42 979-98 PubMed GONUTS page
  2. 2.0 2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. Déziel, E et al. (2004) Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication. Proc. Natl. Acad. Sci. U.S.A. 101 1339-44 PubMed GONUTS page
  4. Xiao, G et al. (2006) Mutation analysis of the Pseudomonas aeruginosa mvfR and pqsABCDE gene promoters demonstrates complex quorum-sensing circuitry. Microbiology (Reading, Engl.) 152 1679-86 PubMed GONUTS page
  5. Déziel, E et al. (2005) The contribution of MvfR to Pseudomonas aeruginosa pathogenesis and quorum sensing circuitry regulation: multiple quorum sensing-regulated genes are modulated without affecting lasRI, rhlRI or the production of N-acyl-L-homoserine lactones. Mol. Microbiol. 55 998-1014 PubMed GONUTS page
  6. Lesic, B et al. (2009) Quorum sensing differentially regulates Pseudomonas aeruginosa type VI secretion locus I and homologous loci II and III, which are required for pathogenesis. Microbiology (Reading, Engl.) 155 2845-55 PubMed GONUTS page