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PSEAE:PILB

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Species (Taxon ID) Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228). (208964)
Gene Name(s) pilB
Protein Name(s) Type 4 fimbrial assembly protein PilB
External Links
UniProt P22608
EMBL M32066
AE004091
PIR A35384
A83081
RefSeq NP_253216.1
ProteinModelPortal P22608
SMR P22608
STRING 208964.PA4526
TCDB 3.A.15.2.1
EnsemblBacteria AAG07914
GeneID 879459
KEGG pae:PA4526
PATRIC 19843783
PseudoCAP PA4526
eggNOG COG2804
HOGENOM HOG000008427
InParanoid P22608
KO K02652
OMA YRPVGCS
OrthoDB EOG63Z76W
PhylomeDB P22608
Proteomes UP000002438
GO GO:0005737
GO:0005524
GO:0008565
GO:0009297
Gene3D 3.40.50.300
InterPro IPR003593
IPR013374
IPR007831
IPR027417
IPR001482
Pfam PF00437
PF05157
SMART SM00382
SUPFAM SSF52540
TIGRFAMs TIGR02538
PROSITE PS00662

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0048870

cell motility

PMID:25049409[1]

ECO:0000315

P

Figure 3c

complete
CACAO 10229

involved_in

GO:0043107

type IV pilus-dependent motility

PMID:25049409[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

GO:0043107

type IV pilus-dependent motility

PMID:25049409[1]

ECO:0000315

P

Figure 3b and c shows the effects of truncated pilb genes. They are unable to restore the twitching ability to the pilB mutant,which implies the deleted regions are necessary for biogenesis of the pili

complete
CACAO 10452

involved_in

GO:0048870

cell motility

PMID:25049409[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0016887

ATPase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001250205
UniProtKB:P22608

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11739
PANTHER:PTN001250205

C

Seeded From UniProt

complete

involved_in

GO:0043683

type IV pilus biogenesis

PMID:1671384[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0043107

type IV pilus-dependent motility

PMID:1671384[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0016887

ATPase activity

PMID:18174131[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013374

F

Seeded From UniProt

complete

enables

GO:0008565

protein transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013374

F

Seeded From UniProt

complete

involved_in

GO:0009297

pilus assembly

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013374

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

involved_in

GO:0015031

protein transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0653

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Chung, IY et al. (2014) A phage protein that inhibits the bacterial ATPase required for type IV pilus assembly. Proc. Natl. Acad. Sci. U.S.A. 111 11503-8 PubMed GONUTS page
  2. 2.0 2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. 3.0 3.1 Strom, MS et al. (1991) Multiple roles of the pilus biogenesis protein pilD: involvement of pilD in excretion of enzymes from Pseudomonas aeruginosa. J. Bacteriol. 173 1175-80 PubMed GONUTS page
  4. Chiang, P et al. (2008) Functional role of conserved residues in the characteristic secretion NTPase motifs of the Pseudomonas aeruginosa type IV pilus motor proteins PilB, PilT and PilU. Microbiology (Reading, Engl.) 154 114-26 PubMed GONUTS page