GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PSEAE:G3XD04
Contents
| Species (Taxon ID) | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 /JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1). (208964) | |
| Gene Name(s) | uvrD (ECO:0000313 with EMBL:AAG08828.1) | |
| Protein Name(s) | DNA helicase (ECO:0000256 with SAAS:SAAS00745194) | |
| External Links | ||
| UniProt | G3XD04 | |
| EMBL | AE004091 | |
| PIR | H82965 | |
| RefSeq | NP_254130.1 WP_003096872.1 | |
| ProteinModelPortal | G3XD04 | |
| SMR | G3XD04 | |
| STRING | 208964.PA5443 | |
| PaxDb | G3XD04 | |
| EnsemblBacteria | AAG08828 | |
| GeneID | 877766 | |
| KEGG | pae:PA5443 | |
| PseudoCAP | PA5443 | |
| eggNOG | ENOG4105C4R COG0210 | |
| InParanoid | G3XD04 | |
| KO | K03657 | |
| OMA | RLQIAFQ | |
| PhylomeDB | G3XD04 | |
| Proteomes | UP000002438 | |
| GO | GO:0005737 GO:0005524 GO:0004003 GO:0003677 GO:0006268 GO:0006298 | |
| InterPro | IPR005753 IPR014017 IPR000212 IPR027417 IPR014016 IPR034739 | |
| PANTHER | PTHR11070 | |
| Pfam | PF00580 PF13361 | |
| SUPFAM | SSF52540 | |
| TIGRFAMs | TIGR01075 | |
| PROSITE | PS51198 PS51217 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0006289 |
nucleotide-excision repair |
ECO:0000315 |
P |
Figure 2 shows two tests supporting UvrD's role in nucleotide excision repair. The first, 2A, shows how the mutant lacking UvrD generated more rifampin-resistant cells as a result of a defective DNA repair system. Then in 2b, cells lacking the UvrD protein had less chance of survival due to increased vulnerability to UV, which is known to cause DNA mutations. Therefore, the UvrD mutants had no repair system to fix the UV mutations. |
complete | |||||
|
enables |
GO:0043140 |
ATP-dependent 3'-5' DNA helicase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10426 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0033202 |
DNA helicase complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000116196 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006281 |
DNA repair |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11064 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10426 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000725 |
recombinational repair |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000116141 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006298 |
mismatch repair |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004003 |
ATP-dependent DNA helicase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000212 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006268 |
DNA unwinding involved in DNA replication |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004386 |
helicase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Martínez, E & Campos-Gómez, J () Pf Filamentous Phage Requires UvrD for Replication in Pseudomonas aeruginosa. mSphere 1 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Oliver, A et al. (2002) The mismatch repair system (mutS, mutL and uvrD genes) in Pseudomonas aeruginosa: molecular characterization of naturally occurring mutants. Mol. Microbiol. 43 1641-50 PubMed GONUTS page
