GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PMID:29202702
| Citation |
Chen, W, Pilling, D and Gomer, RH (2017) C-reactive protein (CRP) but not the related pentraxins serum amyloid P and PTX3 inhibits the proliferation and induces apoptosis of the leukemia cell line Mono Mac 6. BMC Immunol. 18:47 |
|---|---|
| Abstract |
Pentraxins are a family of highly conserved secreted proteins that regulate the innate immune system, including monocytes and macrophages. C-reactive protein (CRP) is a plasma protein whose levels can rise to 1000 μg/ml from the normal <3 μg/ ml during inflammation. |
| Links |
PubMed PMC5716379 Online version:10.1186/s12865-017-0230-z |
| Keywords |
|
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0032945: negative regulation of mononuclear cell proliferation |
ECO:0000314: |
P |
“CRP decreased the numbers of Mono Mac 6 cells at 24 and 48 h (Fig. 1d, e).” Organism: Human |
complete | ||||
Notes
See also
References
See Help:References for how to manage references in GONUTS.
