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PMID:27013840
| Citation |
Biswas, PP, Dey, S, Sen, A and Adhikari, L Molecular Characterization of Virulence Genes in Vancomycin-Resistant and Vancomycin-Sensitive Enterococci. J Glob Infect Dis 8:16-24 |
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| Abstract |
The aim of this study was to find out the correlation between presence of virulence (gelatinase [gel E], enterococcal surface protein [esp], cytolysin A [cyl A], hyaluronidase [hyl], and aggregation substance [asa1]) and vancomycin-resistant genes (van A and van B) in enterococci, with their phenotypic expression. |
| Links |
PubMed PMC4785752 Online version:10.4103/0974-777X.176141 |
| Keywords |
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Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0044085: cellular component biogenesis |
ECO:0000314: |
P |
Table 3 shows the five vancomycin sensitive and resistant genes that were identified in this study using PCR and known genetic sequencing of eneterococci species both from clinical and fecal isolates. The gel E gene was found to be present in a high percentage of vancomysin resistant enterococci species both in clinical isolates (44.4%) and fecal isolates (29.2%) compared to lower percentage isolates being vancomysin sensitive enterococci species. In comparing these percentages they were considered statistical significant allowing these researchers to conclude that the gel E gene that encoded for gelatinase which, is considered a cellular constituent, significantly contributed to these species being vancomycin resistant when compared to enterococci species that didn't as regularly contain the gel E gene being more vancomycin sensitive. |
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Notes
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