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PMID:24567802

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Citation

Seeberger, KL, Anderson, SJ, Ellis, CE, Yeung, TY and Korbutt, GS (2014) Identification and differentiation of PDX1 β-cell progenitors within the human pancreatic epithelium. World J Diabetes 5:59-68

Abstract

To minimize the expansion of pancreatic mesenchymal cells in vitro and confirm that β-cell progenitors reside within the pancreatic epithelium.

Links

PubMed PMC3932428 Online version:10.4239/wjd.v5.i1.59

Keywords


Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

HUMAN:PDX1

GO:0003309: type B pancreatic cell differentiation

ECO:0000315:

P

Figure 2c shows gene expression of PDX1 and insulin in islet cells

complete
CACAO 9903

HUMAN:PDX1

GO:0003309: type B pancreatic cell differentiation

ECO:0000314:

P

Figure 3 shows the differentiated and undifferentiated cells from the islet pancreatic tissues that were infected with PDX1. Very few PDX1+ cells were seen in the differentiated condition. PDX1+ were found in the monolayer in the undifferentiated cell conditions.

complete
CACAO 9904

HUMAN:PDX1

involved_in

GO:0003309: type B pancreatic cell differentiation

ECO:0000314: direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

See also

References

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