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PMID:24206759
| Citation |
Claire D'Andre, H, Paul, W, Shen, X, Jia, X, Zhang, R, Sun, L and Zhang, X (2013) Identification and characterization of genes that control fat deposition in chickens. J Anim Sci Biotechnol 4:43 |
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| Abstract |
Fat deposits in chickens contribute significantly to meat quality attributes such as juiciness, flavor, taste and other organoleptic properties. The quantity of fat deposited increases faster and earlier in the fast-growing chickens than in slow-growing chickens. In this study, Affymetrix Genechip® Chicken Genome Arrays 32773 transcripts were used to compare gene expression profiles in liver and hypothalamus tissues of fast-growing and slow-growing chicken at 8 wk of age. Real-time RT-PCR was used to validate the differential expression of genes selected from the microarray analysis. The mRNA expression of the genes was further examined in fat tissues. The association of single nucleotide polymorphisms of four lipid-related genes with fat traits was examined in a F2 resource population. |
| Links |
PubMed PMC3874612 Online version:10.1186/2049-1891-4-43 |
| Keywords |
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Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004337: geranyltranstransferase activity |
ECO:0000314: |
F |
According to figure 4, fdps genes were upregulated in abdominal fat, subcutaneous fat, and breast muscle tissues in WRR male chickens as opposed to XH male chickens. It can be inferred that the fast growing WRR chickens gain fat and muscle quicker as a result of abnormally upregulated genes, including fdps. Fdps plays a key role in fat and muscle development. |
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