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PMID:24131868
Citation |
Dai, X, Jiang, W, Zhang, Q, Xu, L, Geng, P, Zhuang, S, Petrich, BG, Jiang, C, Peng, L, Bhattacharya, S, Evans, SM, Sun, Y, Chen, J and Liang, X (2013) Requirement for Integrin-linked kinase in neural crest migration and differentiation and outflow tract morphogenesis. BMC Biol. 11:107 |
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Abstract |
Neural crest defects lead to congenital heart disease involving outflow tract malformation. Integrin-linked-Kinase (ILK) plays important roles in multiple cellular processes and embryogenesis. ILK is expressed in neural crest, but its role in neural crest and outflow tract morphogenesis remains unknown. |
Links |
PubMed Online version:10.1186/1741-7007-11-107 |
Keywords |
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Significance
Annotations
Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|
GO:0003151: outflow tract morphogenesis |
ECO:0000315: |
P |
Figure 1 - OFT is observed to be dilated and malformed. |
complete | ||||
involved_in |
GO:0003151: outflow tract morphogenesis |
ECO:0000315: mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
See also
References
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