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PMID:23553854
| Citation |
Tao, G, Miller, LJ and Lincoln, J (2013) Snai1 is important for avian epicardial cell transformation and motility. Dev. Dyn. 242:699-708 |
|---|---|
| Abstract |
Formation of the epicardium requires several cellular processes including migration, transformation, invasion, and differentiation in order to give rise to fibroblast, smooth muscle, coronary endothelial and myocyte cell lineages within the developing myocardium. Snai1 is a zinc finger transcription factor that plays an important role in regulating cell survival and fate during embryonic development and under pathological conditions. However, its role in avian epicardial development has not been examined. |
| Links |
PubMed PMC3668562 Online version:10.1002/dvdy.23967 |
| Keywords |
Animals; Cell Differentiation; Cell Lineage; Cell Movement; Cell Proliferation; Chick Embryo; Gene Expression Regulation, Developmental; Heart/embryology; Matrix Metalloproteinase 15/metabolism; Matrix Metalloproteinases/metabolism; Mice; Myocardium/metabolism; Pericardium/embryology; Pericardium/metabolism; Real-Time Polymerase Chain Reaction; Snail Family Transcription Factors; Transcription Factors/genetics; Transcription Factors/physiology |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0005623: cell |
ECO:0000314: direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0004160)|part_of:(UBERON:0002348) |
Seeded From UniProt |
complete | ||
Notes
See also
References
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