GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PMID:22083550
| Citation |
Widmayer, P, Küper, M, Kramer, M, Königsrainer, A and Breer, H (2012) Altered expression of gustatory-signaling elements in gastric tissue of morbidly obese patients. Int J Obes (Lond) 36:1353-9 |
|---|---|
| Abstract |
Sensing of nutrients in the stomach is of crucial importance for the regulation of ingestive behavior especially in the context of metabolic dysfunctions such as obesity. Cells in the gastric mucosa with taste-signaling elements are considered as candidates for sensing the composition of ingested food and consequently modulate gastrointestinal processes. To assess whether obesity might have an impact on gastric chemosensory cells, gastric tissue samples from morbidly obese patients and normal-weight subjects were compared using a reverse transcriptase (RT)-PCR, qPCR and immunohistochemical approach. |
| Links |
PubMed PMC3466488 Online version:10.1038/ijo.2011.216 |
| Keywords |
|
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0007186: G-protein coupled receptor signaling pathway |
ECO:0000314: |
P |
GPR120 acts as a medium and a long-chain fatty acid receptor. The GPR120 band was stronger in morbidly obese people (Figure 2). This may be linked to higher mRNA levels in these persons (Figure 3). |
complete | ||||
See also
References
See Help:References for how to manage references in GONUTS.
