GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PMID:17573482
| Citation |
Vattanaviboon, P, Tanboon, W and Mongkolsuk, S (2007) Physiological and expression analyses of Agrobacterium tumefaciens trxA, encoding thioredoxin. J. Bacteriol. 189:6477-81 |
|---|---|
| Abstract |
Exposure of Agrobacterium tumefaciens to menadione, cumene hydroperoxide, and diamide strongly induced trxA expression. The trxA mutant showed a reduction in the aerobic growth rate and plating efficiency and was cytochrome c oxidase negative. Atypically, the mutant has decreased resistance to menadione but an increased H2O2 resistance phenotype. |
| Links |
PubMed PMC1951901 Online version:10.1128/JB.00623-07 |
| Keywords |
Agrobacterium tumefaciens/drug effects; Bacterial Proteins/genetics; Benzene Derivatives/pharmacology; Diamide/pharmacology; Gene Expression Regulation, Bacterial; Oxidants/pharmacology; Thioredoxins/genetics; Vitamin K 3/pharmacology |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004791: thioredoxin-disulfide reductase activity |
ECO:0000315: |
F |
By using a knockout mutation of trxA to test in altered oxidative stress resistant environments it was found that the inactivation of the gene caused higher levels of damaging oxidative macromolecules. It can be seen in Figure 1 that thioredoxin is needed under these conditions and TrxA is expressed to produce this macromolecule. |
complete | ||||
See also
References
See Help:References for how to manage references in GONUTS.
