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PMID:12011025
| Citation |
Sundstrom, P, Cutler, JE and Staab, JF (2002) Reevaluation of the role of HWP1 in systemic candidiasis by use of Candida albicans strains with selectable marker URA3 targeted to the ENO1 locus. Infect. Immun. 70:3281-3 |
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| Abstract |
Previous evaluation of HWP1 in systemic candidiasis in CBA/J mice was done with Candida albicans strains with differing genetic locations of URA3 as a result of Ura-blaster mutagenesis. In this study, the presence of HWP1 and the location of URA3 contributed to the severity of murine systemic candidiasis in BALB/c mice. |
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| Keywords |
Animals; Biological Markers; Candida albicans/genetics; Candida albicans/pathogenicity; Candidiasis/microbiology; Candidiasis/mortality; Candidiasis/physiopathology; Disease Models, Animal; Fungal Proteins/genetics; Genes, Fungal; Membrane Glycoproteins/genetics; Membrane Glycoproteins/physiology; Mice; Mice, Inbred BALB C; Phosphopyruvate Hydratase/genetics |
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Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0009405: pathogenesis |
ECO:0000315: mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
Notes
See also
References
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