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PMID:11514017
| Citation |
Józsa, R, Somogyvári-Vigh, A, Reglödi, D, Hollósy, T and Arimura, A (2001) Distribution and daily variations of PACAP in the chicken brain. Peptides 22:1371-7 |
|---|---|
| Abstract |
Levels of PACAP38 were measured in different areas of the chicken brain under various lighting conditions by radioimmunoassay (RIA). Selected groups of animals were maintained under light for 14 h alternating with 10 h of darkness (LD), reversed lighting conditions (DL) and constant light (LL) or constant dark (DD). Daily variations of PACAP levels were observed in the brainstem, diencephalon, telencephalon and retina. In the brainstem and diencephalon, levels of PACAP increased during subjective nighttime, except in the DL group where levels were elevated between 15-21 h. In the telencephalon, the lowest level of PACAP was measured between 12-21 h except in the DL group where two peaks occurred at 18 and 03 h. In the retina, all 4 groups showed a similar level and pattern, with lowest levels during midday hours. No daily variation was observed in the pineal gland. According to the present observations, it is suggested that PACAP levels differ in several areas of the chicken brain under various lighting conditions and photic stimuli do not appear to be the main regulators of the circadian variations of PACAP. |
| Links | |
| Keywords |
Analysis of Variance; Animals; Animals, Newborn; Brain/anatomy & histology; Brain/metabolism; Chickens; Circadian Rhythm; Neuropeptides/metabolism; Photoperiod; Pituitary Adenylate Cyclase-Activating Polypeptide; Radioimmunoassay; Retina/chemistry; Retina/physiology; Time Factors; Tissue Distribution |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0005623: cell |
ECO:0000314: direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0002298)|part_of:(UBERON:0001894)|part_of:(UBERON:0001893)|part_of:(UBERON:0002037)|part_of:(UBERON:0000007)|part_of:(UBERON:0000966)|part_of:(UBERON:0001905) |
Seeded From UniProt |
complete | ||
Notes
See also
References
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