PANTR:H2QD46

Species (Taxon ID)	Pan troglodytes (Chimpanzee). (9598)
Gene Name(s)	BRCA1 (ECO:0000313 with Ensembl:ENSPTRP00000015727)
Protein Name(s)	Breast cancer type 1 susceptibility protein (ECO:0000256 with PIRNR:PIRNR001734)
External Links
UniProt	H2QD46
EMBL	AACZ03110330 AACZ03110331 AACZ03110332 AACZ03110333 AACZ03110334
RefSeq	XP_009430355.1 XP_009430356.1 XP_009430357.1
UniGene	Ptr.6298
STRING	9598.ENSPTRP00000015727
PaxDb	H2QD46
Ensembl	ENSPTRT00000016988
GeneID	449497
CTD	672
eggNOG	ENOG410ITQ6 ENOG4111WR7
GeneTree	ENSGT00440000034289
OMA	FQHLLFG
OrthoDB	EOG79CXXK
TreeFam	TF105060
Proteomes	UP000002277
GO	GO:0070531 GO:0031436 GO:0000794 GO:0005737 GO:0030529 GO:0005886 GO:0003684 GO:0016874 GO:0003723 GO:0044212 GO:0004842 GO:0008270 GO:0071681 GO:0071356 GO:0007098 GO:0043009 GO:0031052 GO:0007059 GO:0006310 GO:0006260 GO:0009048 GO:0031572 GO:0008630 GO:1902042 GO:0045717 GO:0035067 GO:0051572 GO:0051573 GO:0033147 GO:2000378 GO:0045892 GO:0045766 GO:0071158 GO:0045739 GO:0051571 GO:2000617 GO:0051574 GO:2000620 GO:0070512 GO:0031398 GO:0045944 GO:0010575 GO:0006301 GO:0051865 GO:0085020 GO:0044030 GO:0006349 GO:0043627 GO:0010212
Gene3D	3.30.40.10 3.40.50.10190
InterPro	IPR011364 IPR031099 IPR025994 IPR001357 IPR018957 IPR001841 IPR013083 IPR017907
PANTHER	PTHR13763 PTHR13763:SF0
Pfam	PF00533 PF12820 PF00097
PIRSF	PIRSF001734
PRINTS	PR00493
SMART	SM00292 SM00184
SUPFAM	SSF52113
PROSITE	PS50172 PS00518 PS50089

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0071158	positive regulation of cell cycle arrest	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000349139 UniProtKB:P38398	P	Seeded From UniProt	complete
part_of	GO:0070531	BRCA1-A complex	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000349139 UniProtKB:P38398	C	Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:104537 PANTHER:PTN000349139 UniProtKB:P38398	P	Seeded From UniProt	complete
involved_in	GO:0045717	negative regulation of fatty acid biosynthetic process	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000349139 UniProtKB:P38398	P	Seeded From UniProt	complete
involved_in	GO:0043009	chordate embryonic development	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:104537 PANTHER:PTN000349142	P	Seeded From UniProt	complete
involved_in	GO:0035067	negative regulation of histone acetylation	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:104537 PANTHER:PTN000349139	P	Seeded From UniProt	complete
involved_in	GO:0035066	positive regulation of histone acetylation	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:104537 PANTHER:PTN000349139 UniProtKB:P38398	P	Seeded From UniProt	complete
part_of	GO:0031436	BRCA1-BARD1 complex	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000349139 UniProtKB:P38398 WB:WBGene00000264	C	Seeded From UniProt	complete
involved_in	GO:0009048	dosage compensation by inactivation of X chromosome	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:104537 PANTHER:PTN000349142	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000349139 UniProtKB:P38398	C	Seeded From UniProt	complete
enables	GO:0004842	ubiquitin-protein transferase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000349139 TAIR:locus:2133109 UniProtKB:P38398	F	Seeded From UniProt	complete
involved_in	GO:0000724	double-strand break repair via homologous recombination	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000349139 TAIR:locus:2133109 UniProtKB:P38398 WB:WBGene00000264	P	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011364	F	Seeded From UniProt	complete
enables	GO:0004842	ubiquitin-protein transferase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011364	F	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011364	C	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011364 InterPro:IPR031099	P	Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR031099	P	Seeded From UniProt	complete
enables	GO:0008270	zinc ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011364	F	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR018957	F	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0539	C	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
involved_in	GO:0006310	DNA recombination	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0233	P	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F	Seeded From UniProt	complete
part_of	GO:0005694	chromosome	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0158	C	Seeded From UniProt	complete
involved_in	GO:0007049	cell cycle	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0131	P	Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0227	P	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0234	P	Seeded From UniProt	complete
part_of	GO:0005694	chromosome	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0468	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
enables	GO:0004842	ubiquitin-protein transferase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000148759	F	Seeded From UniProt	complete
part_of	GO:0005694	chromosome	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000148759	C	Seeded From UniProt	complete
involved_in	GO:0051865	protein autoubiquitination	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000148759	P	Seeded From UniProt	complete
involved_in	GO:0085020	protein K6-linked ubiquitination	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000148759	P	Seeded From UniProt	complete
part_of	GO:0031436	BRCA1-BARD1 complex	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000148759	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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PANTR:H2QD46

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Annotations

Notes

References

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