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ONCMY:GHRL

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Species (Taxon ID) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri). (8022)
Gene Name(s) ghrl
Protein Name(s) Ghrelin

Ghrelin-23 Ghrelin-24

External Links
UniProt Q76IQ4
EMBL AB096919
AB100839
AB100839
AB101443
RefSeq NP_001118060.1
UniGene Omy.12167
GeneID 100136596
CTD 51738
HOVERGEN HBG018522
GO GO:0005576
GO:0001664
GO:0016608
GO:0007186
GO:0030252
InterPro IPR006737
Pfam PF04643

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0042594

response to starvation

PMID:17466549[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:17466549[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0051480

regulation of cytosolic calcium ion concentration

PMID:12970156[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010628

positive regulation of gene expression

PMID:16614381[3]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(CL:0000234)

Seeded From UniProt

complete

involved_in

GO:1901671

positive regulation of superoxide dismutase activity

PMID:16614381[3]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(CL:0000234)

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:19896947[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0032099

negative regulation of appetite

PMID:19896947[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0030252

growth hormone secretion

PMID:12970156[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0016608

growth hormone-releasing hormone activity

PMID:12970156[2]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9QYH7

F

Seeded From UniProt

complete

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

PMID:12970156[2]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9QYH7

P

Seeded From UniProt

complete

enables

GO:0001664

G protein-coupled receptor binding

PMID:12970156[2]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9QYH7

F

Seeded From UniProt

complete

part_of

GO:0005623

cell

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0051480

C

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0016608

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0016608

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

enables

GO:0005179

hormone activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006737

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005441
InterPro:IPR006737

C

Seeded From UniProt

complete

enables

GO:0016608

growth hormone-releasing hormone activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005441

F

Seeded From UniProt

complete

involved_in

GO:0030252

growth hormone secretion

PMID:12970156[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0051480

regulation of cytosolic calcium ion concentration

PMID:12970156[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010628

positive regulation of gene expression

PMID:16614381[3]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(CL:0000234)

Seeded From UniProt

complete

involved_in

GO:1901671

positive regulation of superoxide dismutase activity

PMID:16614381[3]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(CL:0000234)

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:19896947[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0032099

negative regulation of appetite

PMID:19896947[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005623

cell

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0051480

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

enables

GO:0005179

hormone activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0372

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Jönsson, E et al. (2007) Plasma ghrelin levels in rainbow trout in response to fasting, feeding and food composition, and effects of ghrelin on voluntary food intake. Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. 147 1116-24 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Kaiya, H et al. (2003) Peptide purification, complementary deoxyribonucleic acid (DNA) and genomic DNA cloning, and functional characterization of ghrelin in rainbow trout. Endocrinology 144 5215-26 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Yada, T et al. (2006) Ghrelin stimulates phagocytosis and superoxide production in fish leukocytes. J. Endocrinol. 189 57-65 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Jönsson, E et al. (2010) Ghrelin decreases food intake in juvenile rainbow trout (Oncorhynchus mykiss) through the central anorexigenic corticotropin-releasing factor system. Gen. Comp. Endocrinol. 166 39-46 PubMed GONUTS page