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ONCMY:CP1A3

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Species (Taxon ID) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri). (8022)
Gene Name(s) cyp1a3
Protein Name(s) Cytochrome P450 1A3

CYP1A3 CYP1A1

External Links
UniProt Q92109
EMBL S69277
U62796
M21310
ProteinModelPortal Q92109
SMR Q92109
HOVERGEN HBG106944
GO GO:0005789
GO:0070330
GO:0020037
GO:0005506
Gene3D 1.10.630.10
InterPro IPR001128
IPR017972
IPR002401
IPR008066
Pfam PF00067
PRINTS PR00463
PR01683
PR00385
SUPFAM SSF48264
PROSITE PS00086

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0071615

oxidative deethylation

PMID:19201019[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0009925

basal plasma membrane

PMID:8339279[2]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(CL:0000182)
  • part_of:(UBERON:0006729)

Seeded From UniProt

complete

part_of

GO:0031528

microvillus membrane

PMID:8339279[2]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0001283)

Seeded From UniProt

complete

part_of

GO:0005790

smooth endoplasmic reticulum

PMID:8339279[2]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000182)

Seeded From UniProt

complete

part_of

GO:0005720

nuclear heterochromatin

PMID:8339279[2]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000182)

Seeded From UniProt

complete

part_of

GO:0031965

nuclear membrane

PMID:8339279[2]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000182)

Seeded From UniProt

complete

part_of

GO:0005791

rough endoplasmic reticulum

PMID:8339279[2]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000182)

Seeded From UniProt

complete

part_of

GO:0005623

cell

PMID:8339279[2]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(CL:1000398)
  • part_of:(UBERON:0004820)

Seeded From UniProt

complete

part_of

GO:0048471

perinuclear region of cytoplasm

PMID:8339279[2]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000182)

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:18281257[3]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(CL:0000182)
  • part_of:(CL:1000488)

Seeded From UniProt

complete

involved_in

GO:0071615

oxidative deethylation

PMID:18281257[3]

ECO:0000314

direct assay evidence used in manual assertion

P

  • happens_during:(GO:0009636)
  • occurs_in:(UBERON:0007132)
  • occurs_in:(CL:0002139)
  • occurs_in:(CL:0000236)
  • occurs_in:(CL:0000094)
  • occurs_in:(CL:0000738)
  • occurs_in:(CL:0000182)

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

PMID:10998501[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:1903165

response to polycyclic arene

PMID:10998501[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005506

iron ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR008066
InterPro:IPR036396

F

Seeded From UniProt

complete

enables

GO:0016705

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR017972
InterPro:IPR036396

F

Seeded From UniProt

complete

enables

GO:0016712

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008066

F

Seeded From UniProt

complete

enables

GO:0020037

heme binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR008066
InterPro:IPR036396

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR008066
InterPro:IPR017972
InterPro:IPR036396

P

Seeded From UniProt

complete

enables

GO:0070330

aromatase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.14.14.1

F

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0256

C

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

part_of

GO:0043231

intracellular membrane-bounded organelle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0492

C

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0004497

monooxygenase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0503

F

Seeded From UniProt

complete

part_of

GO:0005789

endoplasmic reticulum membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0097

C

Seeded From UniProt

complete

part_of

GO:0031090

organelle membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0165

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. González, JF et al. () Kinetics of hepatic phase I and II biotransformation reactions in eight finfish species. Mar. Environ. Res. 67 183-8 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 Lester, SM et al. (1993) Hepatic cellular distribution of cytochrome P-450 IA1 in rainbow trout (Oncorhynchus mykiss): an immunohisto- and cytochemical study. Cancer Res. 53 3700-6 PubMed GONUTS page
  3. 3.0 3.1 Nakayama, A et al. (2008) Surface marker-defined head kidney granulocytes and B lymphocytes of rainbow trout express benzo[a]pyrene-inducible cytochrome P4501A protein. Toxicol. Sci. 103 86-96 PubMed GONUTS page
  4. 4.0 4.1 Navas, JM & Segner, H (2000) Antiestrogenicity of beta-naphthoflavone and PAHs in cultured rainbow trout hepatocytes: evidence for a role of the arylhydrocarbon receptor. Aquat. Toxicol. 51 79-92 PubMed GONUTS page